TY  - EJOU
AU  - WANG, LEI 
AU  - WANG, ZHI-HANG 
AU  - CAO, NIAN-PING 
AU  - CHEN, BOBO 
AU  - HUANG, CHONG-JUN 
AU  - YANG, LEI 
AU  - TIAN, YE 

TI  - Estrogen-related receptor alpha: A novel perspective on skeletal, muscular, and vascular systems
T2  - BIOCELL

PY  - 2024
VL  - 48
IS  - 2
SN  - 1667-5746

AB  - Estrogen-related receptor alpha can significantly affect cell metabolism and play key regulatory roles in healthy and diseased organisms. ERRα is also related to the onset and progression of various cancer types. ERRα is primarily expressed in metabolically active tissues and regulates the transcription of metabolic genes in such tissues. It coordinates metabolism and energy demand, affects osteoblasts, osteoclasts, and chondrocytes, promotes muscle regeneration, participates in angiogenesis, and regulates cell aging. In this study, the literature related to the identification of ERRα in skeletal, muscular, and vascular systems was reviewed to further elucidate this receptor.
KW  - Estrogen-related receptor alpha (ERRα); Skeletal muscle; Blood vessel; Osteoporosis; Arthritis

DO  - 10.32604/biocell.2023.045349