TY  - EJOU
AU  - ALZGHOUL, YARA 
AU  - ISSA, HALA J. BANI 
AU  - SANAJLEH, AHMAD K. 
AU  - ALABDUH, TAQWA 
AU  - RABABAH, FATIMAH 
AU  - AL-SHDAIFAT, MAHA 
AU  - ABU-EL-RUB, EJLAL 
AU  - ALMAHASNEH, FATIMAH 
AU  - KHASAWNEH, RAMADA R. 
AU  - ALZU’BI, AYMAN 
AU  - MAGABLEH, HUTHAIFA 

TI  - Therapeutic and regenerative potential of different sources of mesenchymal stem cells for cardiovascular diseases
T2  - BIOCELL

PY  - 2024
VL  - 48
IS  - 4
SN  - 1667-5746

AB  - Mesenchymal stem cells (MSCs) are ideal candidates for treating many cardiovascular diseases. MSCs can modify the internal cardiac microenvironment to facilitate their immunomodulatory and differentiation abilities, which are essential to restore heart function. MSCs can be easily isolated from different sources, including bone marrow, adipose tissues, umbilical cord, and dental pulp. MSCs from various sources differ in their regenerative and therapeutic abilities for cardiovascular disorders. In this review, we will summarize the therapeutic potential of each MSC source for heart diseases and highlight the possible molecular mechanisms of each source to restore cardiac function.
KW  - Bone marrow mesenchymal stem cells; Adipose tissue mesenchymal stem cells; Dental pulp stem cells; Umbilical cord mesenchymal stem cells; Cardiomyocytes; Regeneration; Myocardial infarction; Mesenchymal stem cells; Differentiation; Immunomodulation

DO  - 10.32604/biocell.2024.048056