TY  - EJOU
AU  - YADAV, POOJA 
AU  - CHAUHAN, NAR SINGH 

TI  - Modulatory role of plant-derived metabolites on host-microbiota interactions: personalized therapeutics outlook
T2  - BIOCELL

PY  - 2024
VL  - 48
IS  - 8
SN  - 1667-5746

AB  - A diverse array of microbes in and on the human body constitute the microbiota. These micro-residents continuously interact with the human host through the language of metabolites to dictate the host’s physiology in health and illnesses. Any biotic and abiotic component ensuring a balanced host-microbiota interaction are potential microbiome therapeutic agents to overcome human diseases. Plant metabolites are continually being used to treat various illnesses. These metabolites target the host’s metabolic machinery and host-gut microbiota interactions to overcome human diseases. Despite the paramount therapeutic significance of the factors affecting host-microbiota interactions, a comprehensive overview of the modulatory role of plant-derived metabolites in host-microbiota interactions is lacking. The current review puts an effort into comprehending the role of medicinal plants in gut microbiota modulation to mitigate various human illnesses. It would develop a holistic understanding of host-microbiota interactions and the role of effectors in health and diseases.
KW  - Microbiome therapeutics; Human gut microbiota; Host-microbiota interactions; Personalized therapeutics; Plant metabolites; Human health and diseases

DO  - 10.32604/biocell.2024.051318