Open Access

ARTICLE

Atrial septal defect in adults is associated with airway hyperresponsiveness

Martina Nassif¹, Reindert P. van Steenwijk², Jacqueline M. Hogenhout², Huangling Lu¹, Rianne H.A.C.M. de Bruin‐Bon B Health¹, Alexander Hirsch^1,3, Peter J. Sterk MD, PhD2 | Berto J. Bouma MD, PhD1 | Bart Straver MD, PhD4 | Jan G.P. Tijssen¹, Barbara J.M. Mulder^1,5, Robbert J. de Winter¹

1 Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
2 Department of Respiratory Medicine, Academic Medical Center, Amsterdam, The Netherlands
3 Department of Cardiology and Radiology, Erasmus Medical Center, Rotterdam, The Netherlands
4 Department of Pediatric Cardiology, Academic Medical Center, Amsterdam, The Netherlands
5 Netherlands Heart Institute, Utrecht, The Netherlands

* Corresponding Author: Robbert J. de Winter, MD PhD FESC, Academic Medical Center‐ University of Amsterdam, Department of Cardiology, Room B2‐137, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. Email: