@Article{cmc.2018.03608,
AUTHOR = {Ying  Hu, Qinfei  Ke, Zhe  Li, Wanli  Han, Zhiyong  Yan},
TITLE = {In Situ Synthesis of Cuprous Oxide/Cellulose Nanofibers Gel and Antibacterial Properties},
JOURNAL = {Computers, Materials \& Continua},
VOLUME = {56},
YEAR = {2018},
NUMBER = {3},
PAGES = {517--527},
URL = {http://www.techscience.com/cmc/v56n3/27814},
ISSN = {1546-2226},
ABSTRACT = {Cellulose nanofibers were synthesized by <i>acetobacter xylinum (xylinum 1.1812)</i>. The cellulose nanofibers with 30-90 nm width constructed three-dimension network gel, which could be used as a wound dressing since it can provide moist environment to a wound. However, cellulose nanofibers have no antimicrobial activity to prevent wound infection. To achieve antimicrobial activity, the cellulose nanofibers can load cuprous oxide (Cu<sub>2</sub>O) particles on the surface. The cuprous oxide is a kind of safe antibacterial material. The copper ions can be reduced into cuprous oxides by reducing agents such as glucose, N<sub>2</sub>H<sub>4</sub> and sodium hypophosphite. The cellulose nanofibers network gel was soaked in CuSO<sub>4</sub> solution and filled with copper ions. The cuprous oxide nanoparticles were in situ synthesized by glucose and embedded in cellulose nanofibers network. The morphologies and structure of the composite gel were analyzed by FESEM, FTIR, WAXRD and inductively coupled plasma (ICP). The sizes of Cu<sub>2</sub>O embedded in cellulose nanofibers network are 200-500 nm wide. The peak at 605 cm<sup>−1</sup> attributed to Cu(I)-O vibration of Cu<sub>2</sub>O shits to 611 cm<sup>−1</sup> in the Cu<sub>2</sub>O/ cellulose composite. The Cu<sub>2</sub>O/ cellulose nanofibers composite reveals the obvious characteristic XRD pattern of Cu<sub>2</sub>O and the results of ICP show that the content of Cu<sub>2</sub>O in the composite is 13.1%. The antibacterial tests prove that the Cu<sub>2</sub>O/ cellulose nanofibers composite has the high antibacterial activities which is higher against S. aureus than against E. coli.},
DOI = {10.3970/cmc.2018.03608}
}