@Article{cmc.2021.013390,
AUTHOR = {Nakhim Chea, Yunyoung Nam},
TITLE = {Classification of Fundus Images Based on Deep Learning for Detecting Eye Diseases},
JOURNAL = {Computers, Materials \& Continua},
VOLUME = {67},
YEAR = {2021},
NUMBER = {1},
PAGES = {411--426},
URL = {http://www.techscience.com/cmc/v67n1/41164},
ISSN = {1546-2226},
ABSTRACT = {Various techniques to diagnose eye diseases such as diabetic retinopathy (DR), glaucoma (GLC), and age-related macular degeneration (AMD), are possible through deep learning algorithms. A few recent studies have examined a couple of major diseases and compared them with data from healthy subjects. However, multiple major eye diseases, such as DR, GLC, and AMD, could not be detected simultaneously by computer-aided systems to date. There were just high-performance-outcome researches on a pair of healthy and eye-diseased group, besides of four categories of fundus image classification. To have a better knowledge of multi-categorical classification of fundus photographs, we used optimal residual deep neural networks and effective image preprocessing techniques, such as shrinking the region of interest, iso-luminance plane contrast-limited adaptive histogram equalization, and data augmentation. Applying these to the classification of three eye diseases from currently available public datasets, we achieved peak and average accuracies of 91.16% and 85.79%, respectively. The specificities for images from the eyes of healthy, GLC, AMD, and DR patients were 90.06%, 99.63%, 99.82%, and 91.90%, respectively. The better specificity performances may alert patient in an early stage of eye diseases to prevent vision loss. This study presents a possible occurrence of a multi-categorical deep neural network technique that can be deemed as a successful pilot study of classification for the three most-common eye diseases and can be used for future assistive devices in computer-aided clinical applications.},
DOI = {10.32604/cmc.2021.013390}
}