TY - EJOU AU - Villa-Pulgarin, Juan Pablo AU - Ruales-Torres, Anderson Alberto AU - Arias-Garzón, Daniel AU - Bravo-Ortiz, Mario Alejandro AU - Arteaga-Arteaga, Harold Brayan AU - Mora-Rubio, Alejandro AU - Alzate-Grisales, Jesus Alejandro AU - Mercado-Ruiz, Esteban AU - Hassaballah, M. AU - Orozco-Arias, Simon AU - Cardona-Morales, Oscar AU - Tabares-Soto, Reinel TI - Optimized Convolutional Neural Network Models for Skin Lesion Classification T2 - Computers, Materials \& Continua PY - 2022 VL - 70 IS - 2 SN - 1546-2226 AB - Skin cancer is one of the most severe diseases, and medical imaging is among the main tools for cancer diagnosis. The images provide information on the evolutionary stage, size, and location of tumor lesions. This paper focuses on the classification of skin lesion images considering a framework of four experiments to analyze the classification performance of Convolutional Neural Networks (CNNs) in distinguishing different skin lesions. The CNNs are based on transfer learning, taking advantage of ImageNet weights. Accordingly, in each experiment, different workflow stages are tested, including data augmentation and fine-tuning optimization. Three CNN models based on DenseNet-201, Inception-ResNet-V2, and Inception-V3 are proposed and compared using the HAM10000 dataset. The results obtained by the three models demonstrate accuracies of 98%, 97%, and 96%, respectively. Finally, the best model is tested on the ISIC 2019 dataset showing an accuracy of 93%. The proposed methodology using CNN represents a helpful tool to accurately diagnose skin cancer disease. KW - Deep learning; skin lesion; convolutional neural network; data augmentation; transfer learning DO - 10.32604/cmc.2022.019529