@Article{cmc.2022.020074,
AUTHOR = {José Escorcia-Gutierrez, Jordina Torrents-Barrena, Margarita Gamarra, Natasha Madera, Pedro Romero-Aroca, Aida Valls, Domenec Puig},
TITLE = {A Feature Selection Strategy to Optimize Retinal Vasculature Segmentation},
JOURNAL = {Computers, Materials \& Continua},
VOLUME = {70},
YEAR = {2022},
NUMBER = {2},
PAGES = {2971--2989},
URL = {http://www.techscience.com/cmc/v70n2/44677},
ISSN = {1546-2226},
ABSTRACT = {Diabetic retinopathy (DR) is a complication of diabetes mellitus that appears in the retina. Clinitians use retina images to detect DR pathological signs related to the occlusion of tiny blood vessels. Such occlusion brings a degenerative cycle between the breaking off and the new generation of thinner and weaker blood vessels. This research aims to develop a suitable retinal vasculature segmentation method for improving retinal screening procedures by means of computer-aided diagnosis systems. The blood vessel segmentation methodology relies on an effective feature selection based on Sequential Forward Selection, using the error rate of a decision tree classifier in the evaluation function. Subsequently, the classification process is performed by three alternative approaches: artificial neural networks, decision trees and support vector machines. The proposed methodology is validated on three publicly accessible datasets and a private one provided by Hospital Sant Joan of Reus. In all cases we obtain an average accuracy above 96% with a sensitivity of 72% in the blood vessel segmentation process. Compared with the state-of-the-art, our approach achieves the same performance as other methods that need more computational power. Our method significantly reduces the number of features used in the segmentation process from 20 to 5 dimensions. The implementation of the three classifiers confirmed that the five selected features have a good effectiveness, independently of the classification algorithm.},
DOI = {10.32604/cmc.2022.020074}
}