TY - EJOU AU - El-Habbak, Omar M. AU - Abdelalim, Abdelrahman M. AU - Mohamed, Nour H. AU - Abd-Elaty, Habiba M. AU - Hammouda, Mostafa A. AU - Mohamed, Yasmeen Y. AU - Taifor, Mohanad A. AU - Mohamed, Ali W. TI - Enhancing Parkinson’s Disease Diagnosis Accuracy Through Speech Signal Algorithm Modeling T2 - Computers, Materials \& Continua PY - 2022 VL - 70 IS - 2 SN - 1546-2226 AB - Parkinson’s disease (PD), one of whose symptoms is dysphonia, is a prevalent neurodegenerative disease. The use of outdated diagnosis techniques, which yield inaccurate and unreliable results, continues to represent an obstacle in early-stage detection and diagnosis for clinical professionals in the medical field. To solve this issue, the study proposes using machine learning and deep learning models to analyze processed speech signals of patients’ voice recordings. Datasets of these processed speech signals were obtained and experimented on by random forest and logistic regression classifiers. Results were highly successful, with 90% accuracy produced by the random forest classifier and 81.5% by the logistic regression classifier. Furthermore, a deep neural network was implemented to investigate if such variation in method could add to the findings. It proved to be effective, as the neural network yielded an accuracy of nearly 92%. Such results suggest that it is possible to accurately diagnose early-stage PD through merely testing patients’ voices. This research calls for a revolutionary diagnostic approach in decision support systems, and is the first step in a market-wide implementation of healthcare software dedicated to the aid of clinicians in early diagnosis of PD. KW - Early diagnosis; logistic regression; neural network; Parkinson’s disease; random forest; speech signal processing algorithms DO - 10.32604/cmc.2022.020109