TY  - EJOU
AU  - Zhou, Tao 
AU  - Pan, Yunfeng 
AU  - Lu, Huiling 
AU  - Dang, Pei 
AU  - Guo, Yujie 
AU  - Wang, Yaxing 

TI  - Guided-YNet: Saliency Feature-Guided Interactive Feature Enhancement Lung Tumor Segmentation Network
T2  - Computers, Materials \& Continua

PY  - 2024
VL  - 80
IS  - 3
SN  - 1546-2226

AB  - Multimodal lung tumor medical images can provide anatomical and functional information for the same lesion. Such as Positron Emission Computed Tomography (PET), Computed Tomography (CT), and PET-CT. How to utilize the lesion anatomical and functional information effectively and improve the network segmentation performance are key questions. To solve the problem, the Saliency Feature-Guided Interactive Feature Enhancement Lung Tumor Segmentation Network (Guide-YNet) is proposed in this paper. Firstly, a double-encoder single-decoder U-Net is used as the backbone in this model, a single-coder single-decoder U-Net is used to generate the saliency guided feature using PET image and transmit it into the skip connection of the backbone, and the high sensitivity of PET images to tumors is used to guide the network to accurately locate lesions. Secondly, a Cross Scale Feature Enhancement Module (CSFEM) is designed to extract multi-scale fusion features after downsampling. Thirdly, a Cross-Layer Interactive Feature Enhancement Module (CIFEM) is designed in the encoder to enhance the spatial position information and semantic information. Finally, a Cross-Dimension Cross-Layer Feature Enhancement Module (CCFEM) is proposed in the decoder, which effectively extracts multimodal image features through global attention and multi-dimension local attention. The proposed method is verified on the lung multimodal medical image datasets, and the results show that the Mean Intersection over Union (MIoU), Accuracy (Acc), Dice Similarity Coefficient (Dice), Volumetric overlap error (Voe), Relative volume difference (Rvd) of the proposed method on lung lesion segmentation are 87.27%, 93.08%, 97.77%, 95.92%, 89.28%, and 88.68%, respectively. It is of great significance for computer-aided diagnosis.
KW  - Medical image segmentation; U-Net; saliency feature guidance; cross-modal feature enhancement; cross-dimension feature enhancement

DO  - 10.32604/cmc.2024.054685