TY  - EJOU
AU  - Obradovic, B.  
AU  - Radisic, M.  
AU  - Vunjak-Novakovic, G.  

TI  - Oxygen Transport in Tissue Engineering Systems: Cartilage and Myocardium
T2  - Fluid Dynamics \& Materials Processing

PY  - 2007
VL  - 3
IS  - 3
SN  - 1555-2578

AB  - Efficient transport of oxygen is one of the main requirements in tissue engineering systems in order to avoid cell death in the inner tissue regions and support uniform tissue regeneration. In this paper, we review approaches to design of tissue engineering systems with adequate oxygen delivery for cultivation of cartilage and myocardium, two distinctly different tissue types with respect to the tissue structure and oxygen requirements. Mathematical modeling was used to support experimental results and predict oxygen transport within the cultivated tissues and correlate it to the cell response and tissue properties.
KW  - tissue engineering
KW  -  oxygen transport
KW  -  cartilage
KW  -  myocardium
KW  -  mathematical modeling

DO  - 10.3970/fdmp.2007.003.189