TY - EJOU AU - Xiao, Xinyi AU - Pan, Dongbo AU - Yuan, Jianjun TI - SC-Net: A New U-Net Network for Hippocampus Segmentation T2 - Intelligent Automation \& Soft Computing PY - 2023 VL - 37 IS - 3 SN - 2326-005X AB - Neurological disorders like Alzheimer’s disease have a significant impact on the lives and health of the elderly as the aging population continues to grow. Doctors can achieve effective prevention and treatment of Alzheimer’s disease according to the morphological volume of hippocampus. General segmentation techniques frequently fail to produce satisfactory results due to hippocampus’s small size, complex structure, and fuzzy edges. We develop a new SC-Net model using complete brain MRI images to achieve high-precision segmentation of hippocampal structures. The proposed network improves the accuracy of hippocampal structural segmentation by retaining the original location information of the hippocampus. Extensive experimental results demonstrate that the proposed SC-Net model is significantly better than other models, and reaches a Dice similarity coefficient of 0.885 on Alzheimer’s Disease Neuroimaging Initiative (ADNI) dataset. KW - SC-Net; hippocampus; brain MRI images; image segmentation DO - 10.32604/iasc.2023.041208