@Article{JPM.2021.38.1-2.6,
AUTHOR = {ANU SINGH AND P.K. DUTTA},
TITLE = {Preparation of Chitin-Glucan Microsphere via SprayDrying Technique and their Antibacterial Activity},
JOURNAL = {Journal of Polymer Materials},
VOLUME = {38},
YEAR = {2021},
NUMBER = {1-2},
PAGES = {63--69},
URL = {http://www.techscience.com/jpm/v38n1-2/56041},
ISSN = {0976-3449},
ABSTRACT = {The experiment was designed to examine the microsphere of the chitin-glucan complex. We
formed a chitin-glucan microsphere (ChGMS) from the spray dryer technique. SEM images
observed that shape of ChGMS was spherical. From particle size analyzer and SEM analysis
both showed that the size of particles was in the range of 1.5 to 3.5 µm. It showed amorphous
nature after the formation of microsphere particles of chitin-glucan. The effect of chitin-glucan
complex and ciprofloxacin loaded chitin-glucan microsphere on Bacillus subtilis and Escherichia
coli were also tested. Antibacterial analysis was indicating that the ciprofloxacin loaded chitinglucan microsphere strongly inhibited the growth of bacteria in comparison to the chitin-glucan
solution. From the analysis, we can conclude that the antibacterial property was also dependent
on the size of the chitin-glucan microsphere. Complexation of the chitin-glucan microsphere
with ciprofloxacin improved the antibacterial activity of the chitin-glucan microsphere.},
DOI = {10.32381/JPM.2021.38.1-2.6}
}