TY - EJOU
AU - Tang, Dalin
AU - Zuo, Heng
AU - Yang, Chun
AU - Wu, Zheyang
AU - Huang, Xueying
AU - Rathod, Rahul H.
AU - Tang, Alexander
AU - Billiar, Kristen L.
AU - Geva, Tal
TI - Comparison of Right Ventricle Morphological and Mechanical Characteristics for Healthy and Patients with Tetralogy of Fallot: An In Vivo MRI-Based Modeling Study
T2 - Molecular \& Cellular Biomechanics
PY - 2017
VL - 14
IS - 3
SN - 1556-5300
AB - Patients with repaired tetralogy of Fallot (TOF) account for the majority of cases with late onset right ventricle failure. Comparing TOF patients with healthy people may provide information to address this challenge. Cardiac magnetic resonance (CMR) data were obtained from 16 TOF patients (patient group, PG) and 6 healthy volunteers (healthy group, HG). At begin-of-ejection, better patient group (n=5, BPG) stress was very close to HG stress (54.7±38.4 kPa vs. 51.2±55.7 kPa, p=0.6889) while worse patient group (n=11, WPG) stress was 84% higher than HG stress (p=0.0418). Stress may be used as an indicator to differentiate BPG patients from WPG patients, with further validations.
KW - Heart modeling
KW - cardiac mechanics
KW - normal ventricle
KW - right ventricle
KW - tetralogy of Fallot
DO - 10.3970/mcb.2017.014.137