@Article{mcb.2019.07310,
AUTHOR = {Ali. E. Dabiri, Matthew Martin, Ghassan S. Kassab},
TITLE = {New Concept in Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA)},
JOURNAL = {Molecular \& Cellular Biomechanics},
VOLUME = {17},
YEAR = {2020},
NUMBER = {1},
PAGES = {25--31},
URL = {http://www.techscience.com/mcb/v17n1/38296},
ISSN = {1556-5300},
ABSTRACT = { The world-wide impact of traumatic injury and associated hemorrhage 
on human health and well-being is significant. Methods to manage bleeding from 
sites within the torso, referred to as non-compressible torso hemorrhage (NCTH), 
remain largely limited to the use of conventional operative techniques. The overall 
mortality rate of patients with NCTH is approximately 50%. Studies from the wars 
in Afghanistan and Iraq have suggested that up to 80% of potentially survivable 
patients die as a result of uncontrolled exsanguinating hemorrhage. The 
commercially available resuscitative endovascular balloon occlusion of the aorta 
(REBOA) is a percutaneous device for the rapid control of torso hemorrhage in 
trauma. A compliant balloon is inserted via the femoral artery and inflated in the 
thoracic or abdominal aorta, providing inflow control of the abdomen, pelvis, or 
groin/lower extremities. Recent studies indicate that REBOA carries an inherent 
risk of aortic injury due to over-inflation and possible risk of aortic or iliac artery
rupture. A new approach isto resolve the issue of balloon sizing and over-inflation. 
We propose a novel concept to be used in trauma facility for arterial occlusion to 
eliminate arterial injury and the risk of vascular rupture through real time balloon 
diameter profile measurements to ensure proper inflation. The proposed concept, 
called Smart Resuscitative Endovascular Balloon Occlusion (SREBO) will be 
novel in the following aspects: 1) It will have electrical conductance-based 
navigation technology to target the desired site of balloon deployment in the aorta, 
2) The balloon can determine the time of proper inflation using electrical 
conductance catheter technology. This technology would eliminate the risk of 
arterial rupture and simplify the procedure in the trauma facility or medical clinics
without significant training. The results can be displayed on a handheld device. 
This novel device has the potential to save civilians in trauma or soldiers injured 
on the battlefield.},
DOI = {10.32604/mcb.2019.07310}
}