@Article{mcb.2020.09529,
AUTHOR = {Qi Li, Ningli Wang, Zhicheng Liu, Lin Li, Zhicheng Liu, Wenjia Wang, Xiaoxue Long, Hongfang Song},
TITLE = {Meta-Analysis of the Relationship between Normal Tension Glaucoma, Open-Angle Glaucoma, and Fractional Pressure Reserve},
JOURNAL = {Molecular \& Cellular Biomechanics},
VOLUME = {17},
YEAR = {2020},
NUMBER = {3},
PAGES = {119--137},
URL = {http://www.techscience.com/mcb/v17n3/39483},
ISSN = {1556-5300},
ABSTRACT = {Aim: To investigate the relationship between glaucoma and intraocular
pressure (IOP), intracranial pressure (ICP), trans-laminar cribrosa pressure difference (TLCPD), and the newly proposed fractional pressure reserve (FPR). Methods: Ten articles were analyzed by meta-analysis, and subgroup analysis of three
factors was conducted. Results: The patients with normal tension glaucoma
(NTG) and open-angle glaucoma (OAG) have higher TLCPD and lower ICP than
healthy subjects, with obvious heterogeneity. The greater heterogeneity may arise
from different ICP measurements and from different countries or regions. FPR
performs better than TLCPD in some ways. Conclusion: Both FPR and TLCPD
can be used as indicators of NTG and OAG, and FPR is more effective than
TLCPD in comparisons between different experiments or individuals.},
DOI = {10.32604/mcb.2020.09529}
}