
@Article{mcb.2008.005.229,
AUTHOR = {Abhijit Sinha Roy, Lloyd H. Back, Rupak K. Banerjee},
TITLE = {Evaluation of Compliance of Arterial Vessel Using Coupled Fluid Structure Interaction Analysis},
JOURNAL = {Molecular \& Cellular Biomechanics},
VOLUME = {5},
YEAR = {2008},
NUMBER = {4},
PAGES = {229--246},
URL = {http://www.techscience.com/mcb/v5n4/28472},
ISSN = {1556-5300},
ABSTRACT = {The <i>in vivo</i> and <i>ex vivo</i> compliance of arteries are expected to be closely related and estimated. Fluid-structure interaction analysis can assess the agreement between the two compliances. To evaluate this hypothesis, a pulsatile fluid-structure interaction analysis of blood flow in femoral artery of a dog was conducted using: (1) measured <i>in vivo</i> mean pressure (72.5 mmHg), mean pressure drop (0.59 mmHg), mean velocity (15.1 cm/sec); and (2) <i>ex vivo</i> measurements of non -- linear elastic properties of femoral artery. Additional analyses were conducted for physiological pressures (104.1 and 140.7 mmHg) and blood flow using a characteristic linear pressure -- flow relationship. The computed compliance decreased from 0.198% diameter change/mmHg at 72.5 mmHg to 0.145% diameter change/mmHg at 140.7 mmHg. The computed compliance tends to match well with <i>in vivo</i> compliance of femoral artery at lower pressure but is overestimated at higher pressure. This suggests an alteration in the compliance of the artery during <i>ex vivo</i> elasticity measurements.},
DOI = {10.3970/mcb.2008.005.229}
}



