TY  - EJOU
AU  - Roy, Abhijit Sinha 
AU  - Back, Lloyd H. 
AU  - Banerjee, Rupak K. 

TI  - Evaluation of Compliance of Arterial Vessel Using Coupled Fluid Structure Interaction Analysis
T2  - Molecular \& Cellular Biomechanics

PY  - 2008
VL  - 5
IS  - 4
SN  - 1556-5300

AB  - The <i>in vivo</i> and <i>ex vivo</i> compliance of arteries are expected to be closely related and estimated. Fluid-structure interaction analysis can assess the agreement between the two compliances. To evaluate this hypothesis, a pulsatile fluid-structure interaction analysis of blood flow in femoral artery of a dog was conducted using: (1) measured <i>in vivo</i> mean pressure (72.5 mmHg), mean pressure drop (0.59 mmHg), mean velocity (15.1 cm/sec); and (2) <i>ex vivo</i> measurements of non -- linear elastic properties of femoral artery. Additional analyses were conducted for physiological pressures (104.1 and 140.7 mmHg) and blood flow using a characteristic linear pressure -- flow relationship. The computed compliance decreased from 0.198% diameter change/mmHg at 72.5 mmHg to 0.145% diameter change/mmHg at 140.7 mmHg. The computed compliance tends to match well with <i>in vivo</i> compliance of femoral artery at lower pressure but is overestimated at higher pressure. This suggests an alteration in the compliance of the artery during <i>ex vivo</i> elasticity measurements.
KW  - Hemodynamics
KW  -  fluid-structure interaction
KW  -  femoral artery
KW  -  pressure-flow relation
KW  -  compliance

DO  - 10.3970/mcb.2008.005.229