@Article{mcb.2012.009.077,
AUTHOR = {},
TITLE = {IVUS-Based Computational Modeling and Planar Biaxial Artery Material Properties for Human Coronary Plaque Vulnerability Assessment},
JOURNAL = {Molecular \& Cellular Biomechanics},
VOLUME = {9},
YEAR = {2012},
NUMBER = {1},
PAGES = {77--94},
URL = {http://www.techscience.com/mcb/v9n1/28531},
ISSN = {1556-5300},
ABSTRACT = {Image-based computational modeling has been introduced for vulnerable atherosclerotic plaques to identify critical mechanical conditions which may be used for better plaque assessment and rupture predictions. In vivo patient-specific coronary plaque models are lagging due to limitations on non-invasive image resolution, flow data, and vessel material properties. A framework is proposed to combine intravascular ultrasound (IVUS) imaging, biaxial mechanical testing and computational modeling with fluid-structure interactions and anisotropic material properties to acquire better and more complete plaque data and make more accurate plaque vulnerability assessment and predictions. Impact of pre-shrink-stretch process, vessel curvature and high blood pressure on stress, strain, flow velocity and flow maximum principal shear stress was investigated.},
DOI = {10.3970/mcb.2012.009.077}
}