TY  - EJOU
AU  - Liu, Ruoyu 
AU  - Hu, Yuhao 
AU  - Xu, Jing 
AU  - Cai, Aiting 
AU  - Wu, Anqi 
AU  - Chen, Lin 
AU  - Cai, Weihua 
AU  - Dong, Deping 
AU  - Xu, Henggui 
AU  - Wang, Feng 

TI  - Circulating circRNAs as Potential Biomarkers for Cancers
T2  - Oncologie

PY  - 2021
VL  - 23
IS  - 3
SN  - 1765-2839

AB  - Cancers are diseases with a high mortality rate worldwide. In order to better diagnose and improve the survival rate, many studies have been conducted. In recent years, the role of non-coding RNAs in cancers has been confirmed, and circular RNAs (circRNAs) have attracted much attention. CircRNAs are involved in the occurrence and development of cancers with high stability. Experiments have shown that they can exist stably in peripheral blood. Therefore, the expression of circulating circRNAs can be detected to help diagnose cancers and reflect tumor progression. In this review, we summarized the role of circulating circRNAs in cancers and discussed their potential as biomarkers.
KW  - Circulating circRNAs; plasma; serum; diagnosis biomarkers; cancers

DO  - 10.32604/oncologie.2021.018514