@Article{oncologie.2022.019263,
AUTHOR = {Ismail Bozkurt, Baris Yasar, Mehmet Baran Uslu, Nazan Bozdogan},
TITLE = {A Primary Sacral Melanoma of Unknown Origin: A Case Report},
JOURNAL = {Oncologie},
VOLUME = {24},
YEAR = {2022},
NUMBER = {1},
PAGES = {163--171},
URL = {http://www.techscience.com/oncologie/v24n1/47266},
ISSN = {1765-2839},
ABSTRACT = {Malignant melanoma caused by malignant transformation of melanocytes is associated with high mortality and is
difficult to manage. Metastasis is not uncommon (up to 31% of all cases) and is closely associated with a poor
prognosis. Although rare (4–5%), extracutaneous melanoma has been reported; however, primary malignant melanoma of the sacrum is extremely rare (only three case reports to date). Here, we present a 51-year-old patient
who underwent surgical treatment for a lesion of the spinal canal and associated bony structures; extensive
aggressive resection was required. She underwent partial sacrectomy and lumbo-iliac fixation (to maintain spinal
stability). Pathology revealed malignant melanoma. We discuss the diagnosis, surgical intervention, and postoperative follow-up, which may assist clinicians. Although metastatic malignant melanoma is usually fatal, primary extracutaneous melanoma of the spine may respond well to surgery and adjuvant radiotherapy.},
DOI = {10.32604/oncologie.2022.019263}
}