TY  - EJOU
AU  - Fan, Yaohua 
AU  - Zhu, Xiyan 
AU  - Lan, Qiuping 
AU  - Lou, Fang 
AU  - Zheng, Yu 
AU  - Lou, Haizhou 
AU  - Fang, Yong 
AU  - Jin, Wei 
AU  - Pan, Hongming 
AU  - Wang, Kaifeng 

TI  - Thermal Radiofrequency Ablation as an Adjuvant Therapy for Patients  With Colorectal Liver Metastasis
T2  - Oncology Research

PY  - 2015
VL  - 23
IS  - 5
SN  - 1555-3906

AB  - Radiofrequency ablation (RFA) is a minimally invasive technology for the treatment of liver malignancies 
and is used as an adjuvant therapy in patients with colorectal liver metastasis (CLM). This study enrolled a 
total of 49 CLM patients who underwent RFA treatment. Univariate and multivariate analyses were performed 
using the log-rank test and Cox proportional hazard model, respectively. Univariate analysis showed that 
OS was closely correlated with tumor size, frequency of RFA treatment, resection of the liver lesion, and 
CEA levels before RFA (<i>p</i><0.05). Multivariate analysis revealed that resection of CLM lesions after RFA, 
frequency of RFA treatment, and serum CEA levels before RFA were independent risk factors for the survival 
of CLM patients (<i>p</i><0.05). Tumor lesion size, resection of the liver lesion after RFA, frequency of RFA treatment, and serum CEA levels before RFA may be important prognostic factors of CLM patients treated with 
RFA therapy.
KW  - Liver metastasis; Radiofrequency ablation (RFA); Influence factor

DO  - 10.3727/096504016X14567549091260