
@Article{096504017X14982585511252,
AUTHOR = {Shidan Liu, Jiaxi Luan, Yan Ding},
TITLE = {miR-144-3p Targets FosB Proto-oncogene, AP-1 Transcription Factor Subunit  (FOSB) to Suppress Proliferation, Migration, and Invasion of PANC-1  Pancreatic Cancer Cells},
JOURNAL = {Oncology Research},
VOLUME = {26},
YEAR = {2018},
NUMBER = {5},
PAGES = {683--690},
URL = {http://www.techscience.com/or/v26n5/56681},
ISSN = {1555-3906},
ABSTRACT = {This study aimed to investigate the role of miR-144-3p in pancreatic cancer (PC) carcinogenesis and to explore 
the mechanism of its function in PC. miR-144-3p was downregulated in PC tissues and cells. miR-144-3p 
overexpression significantly inhibited PC cell proliferation, migration, and invasion. FosB proto-oncogene, 
AP-1 transcription factor subunit (FOSB) was a target gene of miR-144-3p. miR-144-3p could repress PC 
cell proliferation, migration, and invasion by inhibiting the expression of FOSB. In conclusion, miR-144-3p 
plays an important role in PC cell proliferation, migration, and invasion by targeting FOSB. miR-144-3p may 
provide a new target for the development of therapeutic agents against PC.},
DOI = {10.3727/096504017X14982585511252}
}



