
@Article{096504018X15152037713570,
AUTHOR = {Jian Ding, Fuqing Wang, Tiangang Xiang, Meng Qiao},
TITLE = {Expression and Function of Long Noncoding RNA NONHSAT129183  in Papillary Thyroid Cancer},
JOURNAL = {Oncology Research},
VOLUME = {26},
YEAR = {2018},
NUMBER = {7},
PAGES = {1047--1053},
URL = {http://www.techscience.com/or/v26n7/56719},
ISSN = {1555-3906},
ABSTRACT = {The aberrant expression of long noncoding RNAs (lncRNAs) is implicated in cancer development and 
progression. This study was aimed to investigate the expression and clinical significance of lncRNA 
NONHSAT129183 in papillary thyroid cancer (PTC), and to explore its roles in PTC cell proliferation, migration, and invasion. Our results demonstrate that lncRNA NONHSAT129183 is upregulated in human PTC tissues when compared with that in adjacent noncancerous thyroid tissue. Moreover, its expression is correlated 
with tumor size, lymph node metastasis, and TNM stage in PTC patients. lncRNA NONHSAT129183 silencing 
also significantly suppressed cell proliferation, migration, and invasion in PTC cell lines. In conclusion, our 
results suggest that lncRNA NONHSAT129183 plays a critical role in the regulation of PTC cell proliferation, 
migration, and invasion, providing new insights into PTC pathogenesis.},
DOI = {10.3727/096504018X15152037713570}
}



