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ARTICLE

A Novel BCL-2 Inhibitor APG-2575 Exerts Synthetic Lethality With BTK or MDM2-p53 Inhibitor in Diffuse Large B-Cell Lymphoma

Qiuyun Luo*†1, Wentao Pan*†‡1, Suna Zhou*†1, Guangfeng Wang, Hanjie Yi, Lin Zhang, Xianglei Yan*†, Luping Yuan*†, Zhenyi Liu#, Jing Wang**, Haibo Chen#, MiaoZhen Qiu*††, DaJun Yang*†‡, Jian Sun*‡‡

* State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou, P.R. China
† Department of Experimental Research, Sun Yat-Sen University Cancer Center, Guangzhou, P.R. China
‡ Suzhou Ascentage Pharma Inc., Jiangsu, P.R. China
§ The Second Affiliated Hospital of Nanchang University, Nanchang, P.R. China
¶ University Department of Clinical Laboratory, Sun Yat-Sen University Cancer Center, Guangzhou, P.R. China
# Peking University Shenzhen Hospital, Shenzhen, P.R. China
** Guangzhou Red Cross Hospital, Guangzhou, P.R. China
†† Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, P.R. China
‡‡ Department of Clinical Research, Sun Yat-Sen University Cancer Center, Guangzhou, P.R. China

TSP_OR_96504020.pdf

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