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cGAS regulates the DNA damage response to maintain proliferative signaling in gastric cancer cells

BIN LIU1,2,#, HAIPENG LIU3,#, FEIFEI REN1,2, HANGFAN LIU1, IHTISHAM BUKHARI1, YUMING FU4, WANQING WU4, MINGHAI ZHAO5, SHAOGONG ZHU6, HUI MO1, FAZHAN LI1,2, MICHAEL B. ZHENG7, YOUCAI TANG1,2, PENGYUAN ZHENG1,2,*, YANG MI1,2,*

1 Henan Key Laboratory of Helicobacter Pylori & Microbiota and Gastrointestinal Cancer, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
2 Academy of Medical Science, Zhengzhou University, Zhengzhou, China
3 Clinical and Translational Research Center, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai, China
4 Gastrointestinal Surgery, The Fifth Affiliated Hospital of Zhengzhou University, Zhengzhou, China
5 Department of Gastrointestinal Surgery, Henan Cancer Hospital, The Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou, China
6 Gastrointestinal Surgery, People Hospital of Zhengzhou University, Zhengzhou, China
7 Faculty of Science, School of Interdisciplinary Science, Honours Life Sciences, McMaster University, Hamilton, ON, Canada

* Corresponding Authors: Pengyuan Zheng, email; Yang Mi, email
# These authors have contributed equally to this work and share the first authorship

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