TY  - EJOU
AU  - Manilal, 
AU  - Selvin, J 
AU  - Shakir, C 
AU  - Kiran, G Seghal 

TI  - Antibacterial activity of <i>Falkenbergia hillebrandii</i> (Born) from the Indian coast against human pathogens
T2  - Phyton-International Journal of Experimental Botany

PY  - 2009
VL  - 78
IS  - all
SN  - 1851-5657

AB  - The antibacterial property of the red algae, <i>Falkenbergia hillebrandii</i> (Born) collected from the southwest coast of India (Indian Ocean) was evaluated against three multidrug resistant human pathogens. Four different solvents: ethyl acetate, dichloromethane, methanol and phosphate buffer saline (PBS) were used with this purpose. Dried samples extracted with methanol showed broadest and highest antimicrobial activity when compared to other solvents. However, PBS extract showed no antibacterial activity. The highly active compounds red alga, <i>F. hillebrandii</i> were fractionated and purified using different chromatographic systems, including reverse phase HPLC and GCMS. The analysis revealed that the most abundant metabolite was the oleic acid (51.33%) followed by n-hexadecanoic acid (42%).
KW  - Antimicrobial activity
KW  -  <i>F. hillebrandii</i>
KW  -  Multidrug resistant human pathogens
KW  -  Methanolic extract
KW  -  Bioactive compounds

DO  - 10.32604/phyton.2009.78.161