@Article{phyton.2020.09420,
AUTHOR = {Jaswinder Kaur, Manish Vyas, Joginder Singh, Ram Prasad, Jeena Gupta},
TITLE = {Therapeutic Applications of Naringenin, a Flavanone Enriched in Citrus Fruits, for Disorders beyond Diabetes},
JOURNAL = {Phyton-International Journal of Experimental Botany},
VOLUME = {89},
YEAR = {2020},
NUMBER = {4},
PAGES = {795--803},
URL = {http://www.techscience.com/phyton/v89n4/40522},
ISSN = {1851-5657},
ABSTRACT = {In recent years, there has been an increase in epidemiological studies to
highlight the health benefits of plant secondary metabolites. Flavonoids (polyphenolic plant secondary metabolites) are recently emerging as an important source
for the discovery of new drugs increasing their pharmaceuticals, nutraceutical
and medicinal applications. Naringenin is a flavanone, enriched in citrus fruits,
tomatoes, bergamot, etc. which has been evaluated extensively for managing
diabetes. However, in addition to this, naringenin had been ascribed to various important biological activities like antioxidant, antiviral, anticancer, anti-inflammatory,
antiestrogenic, etc. This article aims at highlighting the therapeutic value of
naringenin in managing disorders other than diabetes and its role in regulating
gene expression by altering chromatin structure as histone deacetylase inhibitor.
The understanding of these phenomena will increase the overall knowledge of
the various health-promoting effects of citrus fruits.},
DOI = {10.32604/phyton.2020.09420}
}