TY  - EJOU
AU  - Raal, Ain 
AU  - Orav, Anne 
AU  - Ilina, Tetiana 
AU  - Kovalyova, Alla 
AU  - Koliadzhyn, Taras 
AU  - Avidzba, Yuliia 
AU  - Koshovyi, Oleh 

TI  - Variation in the Composition of the Essential Oil of Commercial <i>Salvia officinalis</i> L. Leaves Samples from Different Countries
T2  - Phyton-International Journal of Experimental Botany

PY  - 2024
VL  - 93
IS  - 8
SN  - 1851-5657

AB  - <i>Salvia officinalis</i> L. (Lamiaceae) leaves and its essential oil is used for mouth and throat disorders, skin disorders, minor wounds, and gastrointestinal disorders, and is widely used worldwide. The research aimed to conduct a comparative study of the composition of <i>S. officinalis</i> essential oils from commercial samples, and their main chemotypes. The volatile constituents from <i>S. officinalis</i> leaves were investigated using gas chromatography (GC). The commercial samples of sage leaves were obtained from retail pharmacies in nine mainly European countries. The yield of essential oil in <i>S. officinalis</i> commercial leaves was between 10.0 and 24.8 mL/kg. The principal components (>5%) among the main identified 25 compounds were 1,8-cineole (8.3%–45.3%), α-thujone (3.0%–34.0%), сamphor (11.3%–29.3%), β-thujone (1.5%–12.9%), viridiflorol (1.1%–10.4%), camphene (2.6%–7.1%), and α-pinene (1.3%–5.8%). In seven (Estonia, England, France, Hungary, Belgium, Ukraine, Georgia) samples α-thujone dominated. Four samples (Estonia, Georgia, England, Hungary) belong to the most common chemotype α-thujone > camphor > 1,8-cineole. Eight chemotypes of <i>S. officinalis</i> essential oils have been found. Toxic thujones are widespread compounds among them.
KW  - Sage; terpenoids; chemotypes; thujone; toxicity

DO  - 10.32604/phyton.2024.052790