TY  - EJOU
AU  - Lin, Chen 
AU  - Zhang, Zidan 
AU  - Zhang, Zhao 
AU  - Long, Yuxiang 
AU  - Shen, Xuwen 
AU  - Zhang, Jinghao 
AU  - Wang, Youping 

TI  - The Role of Glutathione S-Transferase in the Regulation of Plant Growth, and Responses to Environmental Stresses
T2  - Phyton-International Journal of Experimental Botany

PY  - 2025
VL  - 94
IS  - 3
SN  - 1851-5657

AB  - Glutathione S-transferases (GSTs) represent a large and diverse enzyme family ubiquitously distributed across the plant kingdom. These proteins catalyze the conjugation of glutathione (GSH) with electrophilic substrates in response to various stress conditions. Beyond their role in stress adaptation, certain GSTs are integral regulators of plant growth and development, contributing to a range of physiological processes. Most GST proteins exhibit dual enzymatic activities, functioning as both transferases and peroxidases, which enables their involvement in diverse cellular processes, including detoxification and stress responses. Recent advancements, particularly in X-ray crystallography, have enabled detailed structural analysis of GST proteins, significantly enhancing our understanding of their biological functions. This review offers a comprehensive overview of the classification and structural characteristics of GSTs in plants. It also highlights recent findings on their roles in plant growth and development, cell signaling, catalytic transport, and stress tolerance. Furthermore, key scientific challenges related to GSTs are discussed, focusing on their potential applications in agriculture. These insights aim to facilitate the screening of functional GST genes and support molecular breeding efforts across diverse crop species.
KW  - Glutathione S-transferase; biotic and abiotic stress; plant growth and development; signal transduction; biological functions

DO  - 10.32604/phyton.2025.063086