TY  - EJOU
AU  - Wang, Tao 
AU  - Wei, Yangyang 
AU  - Li, Pengtao 
AU  - Liu, Yuling 
AU  - Song, Hui 
AU  - Peng, Renhai 

TI  - Genome-Wide Identification of the <i>KCS</i> Gene Family in Foxtail Millet (<i>Setaria italica</i> L.)
T2  - Phyton-International Journal of Experimental Botany

PY  - 2026
VL  - 95
IS  - 4
SN  - 1851-5657

AB  - Very long-chain fatty acids (VLCFAs) are widely distributed across plant tissues. 3-Ketoacyl-CoA synthase (KCS) is one of the most crucial enzymes in VLCFA synthesis and markedly influences fatty acid composition in plants. However, the relevant information on KCS proteins in foxtail millet remains poorly understood. In the current study, 30 <i>KCS</i> genes were found in foxtail millet using bioinformatics methods. Phylogenetic data indicated that these genes cluster into eight distinct groups, with members of each group sharing similar motif structures. Further analysis revealed that the <i>cis</i>-acting elements of <i>SiKCS</i> genes are mainly involved in growth and developmental processes. Synteny analysis indicates that segmental duplications are crucial for the expansion of the <i>KCS</i> genes. Expression profiles results indicated that 22 <i>SiKCSs</i> were highly expressed in the foxtail millet seed. This comprehensive analysis provided important insights for the functions of <i>KCS</i> genes and identified potential genetic resources for precision breeding enhancement in foxtail millet.
KW  - Foxtail millet; very long-chain fatty acid; <i>KCS</i> gene family; genome-wide analysis

DO  - 10.32604/phyton.2026.078858