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  • Open Access

    ARTICLE

    Is cystoscopy indicated for incidentally identified bladder wall thickening?

    Daniel S. McPartlin1,2, Adam P. Klausner1,2, Charles U. Nottingham1, Jeffrey P. Wolters1, Albert Petrossian1, Laura R. Carucci3, B. Mayer Grob1,2

    Canadian Journal of Urology, Vol.20, No.1, pp. 6615-6619, 2013

    Abstract Introduction: The purpose of this study was to evaluate the yield of cystoscopy in detecting bladder malignancy following incidentally identified bladder wall thickening observed on computed tomography (CT) scans.
    Methods and materials: Data from 3000 consecutive patients who underwent diagnostic cystoscopy at a single institution from 2006-2009 were collected retrospectively. All prior CT scan reports were reviewed, and patients whose sole indication for cystoscopy was incidentally detected bladder wall thickening were identified. Patients were categorized as diffuse thickening, focal thickening, or focal bladder mass based on the radiologist's report. Collected data included patient age, gender, race, smoking… More >

  • Open Access

    ARTICLE

    Lactobacillus for preventing recurrent urinary tract infections in women: meta-analysis

    Peter M. Grin1,2, Paulina M. Kowalewska3, Waleed Alhazzani1, Alison E. Fox-Robichaud1,2

    Canadian Journal of Urology, Vol.20, No.1, pp. 6607-6614, 2013

    Abstract Introduction: Urinary tract infections (UTIs) are the most common infections affecting women, and often recur. Lactobacillus probiotics could potentially replace low dose, long term antibiotics as a safer prophylactic for recurrent UTI (rUTI). This systematic review and meta-analysis was performed to compile the results of existing randomized clinical trials (RCTs) to determine the efficacy of probiotic Lactobacillus species in preventing rUTI.
    Materials and methods: MEDLINE and EMBASE were searched from inception to July 2012 for RCTs using a Lactobacillus prophylactic against rUTI in premenopausal adult women. A random-effects model meta-analysis was performed using a pooled risk ratio,… More >

  • Open Access

    ARTICLE

    High pressure vaginography to diagnose vaginal ureteral ectopia in patients with continuous urinary incontinence

    Jack M. Zuckerman, Bijan Shekarriz, Jyoti Upadhyay

    Canadian Journal of Urology, Vol.20, No.1, pp. 6603-6606, 2013

    Abstract Introduction: Continuous urinary incontinence in female patients can be a diagnostic dilemma if traditional imaging fails to identify a source. Vaginography has been used to diagnose vaginal ectopic ureters in the past with mixed results.
    Materials and methods: Institutional review board approval was obtained for a retrospective review. Five teenage females with continuous incontinence and prior negative imaging work ups underwent high pressure vaginography. Their findings and treatment outcomes are reviewed.
    Results: A vaginal ectopic ureter was diagnosed in each of the five patients at a mean age 15.8 years. Each had undergone prior magnetic resonance urography that More >

  • Open Access

    ARTICLE

    The influence of PSA-RNA yield on the analysis of expressed prostatic secretions (EPS) for prostate cancer diagnosis

    Christopher Whelan1, Laura Crocitto1, Mark Kawachi1, Kevin Chan1, David Smith2, Timothy Wilson1, Steven Smith1,3

    Canadian Journal of Urology, Vol.20, No.1, pp. 6597-6602, 2013

    Abstract Introduction: In patients with prostate cancer, luminal prostate-specific antigen (PSA) enters the circulation because the basement membrane and glandular epithelium are damaged. Given that excess mobilization of prostate cells during prostatic massage can influence normalization in diagnostic testing, we studied PSA mRNA levels in expressed prostatic secretions (EPS) from patients undergoing biopsy for prostate cancer to determine if prostate cells are preferentially mobilized from patients with prostate cancer during prostatic massage.
    Materials and methods: Quantitative Reverse-Transcription PCR (qRT-PCR) was used to measure the RNA levels of GAPDH, PSA, TMPRSS2:ERG and PCA3 in EPS specimens obtained from patients… More >

  • Open Access

    LEGENDS IN UROLOGY

    LEGENDS IN UROLOGY

    William L. Parry

    Canadian Journal of Urology, Vol.20, No.1, pp. 6593-6596, 2013

    Abstract This article has no abstract. More >

  • Open Access

    EDITORIAL

    CAUTI and Readmission Penalties: Urologists Beware

    Leonard G. Gomella

    Canadian Journal of Urology, Vol.20, No.1, pp. 6592-6592, 2013

    Abstract This article has no abstract. More >

  • Open Access

    COMMENTARY

    Percutaneous renal biopsy may aid management of small renal masses on active surveillance

    Jay D. Raman

    Canadian Journal of Urology, Vol.20, No.2, pp. 6742-6742, 2013

    Abstract This article has no abstract. More >

  • Open Access

    RESIDENT’S CORNER

    Explosive growth of a renal tumor during active surveillance

    Matthew A. Uhlman, Scott C. Pate, James A. Brown

    Canadian Journal of Urology, Vol.20, No.2, pp. 6739-6741, 2013

    Abstract The incidence of small renal masses (≤ 4 cm) has increased over the past three decades. Partial nephrectomy remains the standard for treatment of such lesions, but increased attention is being given to patients who may benefit from active surveillance, given the low risk of metastatic spread and traditionally slow growth rates. Patients with significant comorbidities and the elderly are often considered optimal candidates for surveillance. We present an 86-year-old female undergoing active surveillance for a 1.4 cm lesion that grew in diameter approximately 0.5 cm per year over 3 years, followed by explosive growth More >

  • Open Access

    RESIDENT’S CORNER

    Metanephric adenofibroma

    Robert M. Turner II1,3, Jeffrey J. Tomaszewski1,3, Janelle A. Fox1,3, Csaba Galambos2,3, Glenn M. Cannon Jr1,3

    Canadian Journal of Urology, Vol.20, No.2, pp. 6737-6738, 2013

    Abstract A 10-year-old boy underwent a computed tomography (CT) scan for left flank pain following a fall. Imaging demonstrated a 5 cm left upper pole renal mass. Partial nephrectomy revealed metanephric adenofibroma, a benign stromal-epithelial tumor thought to represent a hyperdifferentiated, mature form of Wilms’ tumor. We briefly discuss the histopathology and management of this rare tumor. More >

  • Open Access

    RESIDENT’S CORNER

    Primary synovial sarcoma of the kidney with unusual follow up fndings

    Ricardo Pereira e Silva1, Tito Leitão1, Lurdes Correia2, Francisco Martins1, José Palma dos Reis1, Tomé Lopes1

    Canadian Journal of Urology, Vol.20, No.2, pp. 6734-6736, 2013

    Abstract We present a case report of a 17-year-old patient with a large renal mass that was detected on a computed tomography scan during investigation for secondary hypertension. Radical nephrectomy was performed, and the morphologic and immunocytochemical findings were compatible with a diagnosis of monophasic synovial sarcoma of the kidney. A cytogenetic search for t(X;18) translocation was performed, which was negative. The patient underwent an ifosfamide-based chemotherapy regimen. During follow-up, a positron emission tomography scan showed increased 18F-fluorodeoxyglucose metabolism at the right femur. Although cancer cells were expected in the biopsy specimen, only fibrous dysplasia of More >

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