Mark D. Tyson II1, Alan H. Bryce2, Thai H. Ho2,
Estrella M. Carballido2, Erik P. Castle1
Canadian Journal of Urology, Vol.21, No.3, pp. 7259-7265, 2014
Abstract Introduction: Few data on the perioperative outcomes of cystectomy after neoadjuvant chemotherapy (NAC) exist. In this study, we evaluated whether patients who had previously received NAC were at higher risk of developing perioperative complications.
Materials and methods: The National Surgical Quality Improvement Program (NSQIP) database was searched to identify cystectomies performed between January 1, 2005 and December 31, 2011. Of 1394 patients identified, about one-tenth (n = 122 [8.8%]) received NAC. A propensity-weighted comparative analysis of perioperative morbidity was conducted.
Results: In unadjusted comparisons, patients undergoing cystectomy after NAC were more likely to have peripheral nerve deficits (1.6%… More >