Mujeebu Rehman¹, Qinghua Liu¹, Ali Ghulam², Tariq Ahmad³, Jawad Khan^4,*, Dildar Hussain^5,*, Yeong Hyeon Gu⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.145, No.1, pp. 779-805, 2025, DOI:10.32604/cmes.2025.067412 - 30 October 2025

Abstract Identifying druggable proteins, which are capable of binding therapeutic compounds, remains a critical and resource-intensive challenge in drug discovery. To address this, we propose CEL-IDP (Comparison of Ensemble Learning Methods for Identification of Druggable Proteins), a computational framework combining three feature extraction methods Dipeptide Deviation from Expected Mean (DDE), Enhanced Amino Acid Composition (EAAC), and Enhanced Grouped Amino Acid Composition (EGAAC) with ensemble learning strategies (Bagging, Boosting, Stacking) to classify druggable proteins from sequence data. DDE captures dipeptide frequency deviations, EAAC encodes positional amino acid information, and EGAAC groups residues by physicochemical properties to generate… More >

Meng Wang¹, Jay Fineberg², Alan Needleman^3,*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-1, 2025, DOI:10.32604/icces.2025.011000

Abstract Brittle materials fail by means of rapid cracks. At their tips, tensile cracks dissipate elastic energy stored in the surrounding material to create newly fractured surfaces, precisely maintaining 'energy balance' by exactly equating the energy flux with dissipation. Using energy balance, fracture mechanics perfectly describes crack motions; accelerating from nucleation to their maximal speed of cR, the Rayleigh wave speed. A tensile crack speed greater than cR is generally considered impossible [1]. Recently, a new mode of tensile crack propagation faster than cR that is not incorporated in classical fracture mechanics has been predicted in… More >

Zheng Zhang¹, Gan-Yun Huang^1,*, Fei Shen^1,2, Liao-Liang Ke¹

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-2, 2025, DOI:10.32604/icces.2025.010965

Abstract Rolling element bearings are critical components in modern industrial machinery, with rolling contact fatigue (RCF) emerging as the predominant failure mode even under optimal installation, lubrication, and maintenance conditions [1–5]. In the paper, a phase field model coupling plasticity and fatigue is developed to investigate spalling behavior under RCF loading. Fatigue crack nucleation, propagation, and bifurcation can be effectively predicted using the phase field model based on theories of energy minimization [6–8]. A numerical framework is established by using the finite element method with an explicit integration scheme. The subsurface initiated spalling, the crack evolution, More >

Xiaoai Yi, Jia Li^*, Qihong Fang^*

The International Conference on Computational & Experimental Engineering and Sciences, Vol.33, No.4, pp. 1-1, 2025, DOI:10.32604/icces.2025.010725

Abstract The complex concentration alloys are considered to have excellent mechanical properties due to the combined effects of heterogeneous composition and microstructure. However, it is difficult for existing simulation methods to capture the significant modulation of mechanical properties by the formation and motion of grain boundaries of complex concentration alloys at the microsecond and nanometer scales. To address this, we utilize the phase field crystal model that combines molecular dynamics and traditional phase field advantages to systematically study real-time grain boundary formation and motion in complex concentration alloys [1]. Meanwhile, we investigated the compositional fluctuations of More >

Zhi-Yun Zhang^1,*, Yaqiong Wu¹, Chenshi Deng², Peng Wang³, Weiguaju Nong^4,*

International Journal of Mental Health Promotion, Vol.27, No.10, pp. 1533-1551, 2025, DOI:10.32604/ijmhp.2025.070883 - 31 October 2025

Abstract Objectives: Medical students often rely on recreational internet media to relieve the stress caused by immense academic and life pressures, and among these media, short-form videos, which are an emerging digital medium, have gradually become the mainstream choice of students to relieve their stress. However, the addiction caused by their usage has attracted the widespread attention of both academia and society, which is why the purpose of this study is to systematically explore the underlying mechanisms that link perceived stress, entertainment gratification, emotional gratification, short-form video usage intensity, and short-form video addiction based on multiple… More >

Yumeng Kong^*, Xuesong Guo, Yifei Wang

International Journal of Mental Health Promotion, Vol.27, No.10, pp. 1577-1594, 2025, DOI:10.32604/ijmhp.2025.069985 - 31 October 2025

Abstract Background: Anxiety and depression are prevalent among university students, calling for effective non-pharmacological interventions. Tai Chi shows potential in reducing these symptoms, but research on its effects at different frequencies in younger populations is limited. This study compared the impacts of high-(5 sessions/week), medium-(3 sessions/week), and low-frequency (2 sessions/week) 24-form Tai Chi on college students’ anxiety/depression, versus a control group. Methods: A randomized controlled trial (RCT) included 120 university students with mild-to-moderate anxiety/depression, randomly assigned to 4 groups (30 each). The 8-week intervention used the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) for… More >

Ceren Ayşe Bayram^*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3283-3295, 2025, DOI:10.32604/phyton.2025.073047 - 29 October 2025

Abstract In semi-arid regions where climatic limitations hinder open-field vegetable production, greenhouse-based lettuce (Lactuca sativa L.) cultivation plays a vital role in ensuring off-season supply. In this study, the potential of sustainable input combinations was evaluated to enhance lettuce productivity, quality, and profitability under unheated greenhouse conditions in Southeastern Türkiye. Treatments included farmer practice and a mycorrhizal biofertilizer (ERS, a water-soluble arbuscular mycorrhizal fungus product) applied alone or in combination with organic-based biostimulants (IS and NM). Evaluated parameters were plant height, leaf pigmentation (a*, h°), SPAD values, vitamin C, nitrogen and phosphorus content, and gross margin. The More >

Başak Müftüoğlu, Sevinç Başay^*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3217-3229, 2025, DOI:10.32604/phyton.2025.071755 - 29 October 2025

Abstract Water scarcity is an escalating global challenge that severely threatens productivity and reproductive success in crops, particularly in drought-sensitive species such as Capsicum annuum L. Although deficit irrigation strategies are widely recommended to enhance water use efficiency, knowledge remains limited regarding their interactions with soil amendments such as biochar and the consequent impacts on reproductive traits. This study aimed to evaluate the combined effects of deficit irrigation strategies and biochar application on pollen viability and morphology in Capsicum annuum. The experiment was conducted under full, partial, and deficit irrigation regimes with and without biochar treatment, following a… More >

Ivica Delic¹, Goran Jukic², Ivan Varnica², Valentina Spanic^3,*

Phyton-International Journal of Experimental Botany, Vol.94, No.10, pp. 3189-3203, 2025, DOI:10.32604/phyton.2025.070489 - 29 October 2025

Abstract This study evaluated agro-morphological traits, grain quality traits, and phenotypic stability of nine soybean genotypes across four environments over two growing seasons (2022–2023). Traits such as days to flowering, days to maturity, and disease symptoms were monitored throughout the season. At maturity, parameters including grain yield, grain oil and protein content, 1000-seed weight, test weight, scores of lodgings, shattering, plant height, and first pod height were evaluated. In addition, 18 morphological traits were scored, of which eight were sufficiently variable for further analysis. In terms of environmental stability, genotypes 2 and 13 excelled, while genotypes… More >

Zhengzheng Cao^1,2,3, Fangxu Guo¹, Wenqiang Wang^2,3,4,*, Feng Du^2,3,4, Zhenhua Li^2,3,4, Shuaiyang Zhang¹, Qixuan Wang¹, Yongzhi Zhai¹

FDMP-Fluid Dynamics & Materials Processing, Vol.21, No.10, pp. 2419-2442, 2025, DOI:10.32604/fdmp.2025.070624 - 30 October 2025

Abstract With the depletion of shallow mineral resources, mining operations are extending to greater depths and larger scales, increasing the risk of water inrush disasters, particularly from confined aquifers intersected by faults. This paper reviews the current state of research on fault-induced water inrushes in mining faces, examining the damage characteristics and permeability of fractured floor rock, the mechanical behavior of faults under mining stress, and the mechanisms driving water inrush. Advances in prevention technologies, risk assessment, and prediction methods are also summarized. Research shows that damage evolution in fractured floor rock, coupled with fluid-solid interactions,… More > Graphic Abstract