Longling Fan^1,§, Jing Yao^2,§, Chun Yang³, Di Xu², Dalin Tang^1,4*

Molecular & Cellular Biomechanics, Vol.13, No.1, pp. 33-55, 2016, DOI:10.3970/mcb.2016.013.044

Abstract Modeling ventricle active contraction based on in vivo data is extremely challenging because of complex ventricle geometry, dynamic heart motion and active contraction where the reference geometry (zero-stress geometry) changes constantly. A new modeling approach using different diastole and systole zero-load geometries was introduced to handle the changing zero-load geometries for more accurate stress/strain calculations. Echo image data were acquired from 5 patients with infarction (Infarct Group) and 10 without (Non-Infarcted Group). Echo-based computational two-layer left ventricle models using one zero-load geometry (1G) and two zero-load geometries (2G) were constructed. Material parameter values in Mooney-Rivlin… More >

Jui-Hsiang Kao¹

CMES-Computer Modeling in Engineering & Sciences, Vol.112, No.1, pp. 59-73, 2016, DOI:10.3970/cmes.2016.112.059

Abstract In this paper, a step approach method in the time domain is developed to calculate the radiated waves from an arbitrary obstacle pulsating with multiple frequencies. The computing scheme is based on the Boundary Integral Equation and derived in the time domain; thus, the time-harmonic Neumann boundary condition can be imposed. By the present method, the values of the initial conditions are set to zero, and the approach process is carried forward in a loop from the first time step to the last. At each time step, the radiated pressure on each element is updated. More >

Ryan Weisman³, Manoranjan Majji⁴, Kyle T. Alfriend⁵

CMES-Computer Modeling in Engineering & Sciences, Vol.111, No.3, pp. 269-304, 2016, DOI:10.3970/cmes.2016.111.269

Abstract This paper presents a closed form solution to Liouville's equation governing the evolution of the probability density function associated with the motion of a body in a central force field and subject to J2. It is shown that the application of transformation of variables formula for mapping uncertainties is equivalent to the method of characteristics for computing the time evolution of the probability density function that forms the solution of the Liouville's partial differential equation. The insights derived from the nature of the solution to Liouville's equation are used to reduce the dimensionality of uncertainties More >

V. Vittaldev¹, R. P. Russell²

CMES-Computer Modeling in Engineering & Sciences, Vol.111, No.1, pp. 83-117, 2016, DOI:10.3970/cmes.2016.111.083

Abstract Monte Carlo simulations are an accurate but computationally expensive procedure for approximating the resultant non-Gaussian probability density function (PDF) after propagation of an initial Gaussian PDF through a nonlinear function. Univariate splitting libraries for Gaussian Mixture Models (GMMs) exist with up to five elements in the literature. The number of splits are extended in the present work by generating three homoscedastic univariate splitting libraries with up to 39 elements. Mulitvariate GMMs are typically handled with splits along a single direction. Instead, we generate a regular multidirectional grid over the initial multivariate Gaussian distribution by recursively… More >

Meryem NAOUM¹, Mustapha EL ALAMI²

FDMP-Fluid Dynamics & Materials Processing, Vol.12, No.2, pp. 56-68, 2016, DOI:10.3970/fdmp.2016.012.056

Abstract A numerical study of mixed convection from a U-shaped channel is carried out. The flow is considered two dimensionnel. The inlet opening is adjusted in the right vertical part of the channel, while the outlet one is placed on the left vertical part. Navier–Stokes equations are solved using a control volume method and the SIMPLEC algorithm is considered for the treatment of pressure–velocity coupling. Special emphasis is given to detail the effect of the Reynolds and Rayleigh numbers on the heat transfer generated by mixed convection. The results are given for the parameters of control More >

Lior M. Hirsch¹, Michael J. Amirian¹, Scott G. Hubosky¹, Akhil K. Das¹, Babak Abai², Costas D. Lallas¹

Canadian Journal of Urology, Vol.22, No.1, pp. 7661-7665, 2015

Abstract Patients with a uretero-iliac artery fistula (UIAF) are at an elevated risk of life-threatening hemorrhage. Identification and treatment of the fistula may be challenging, and requires the combined expertise of a urologist and endovascular specialist. This manuscript provides a list of equipment needed and describes our technique for diagnosing and treating a UIAF. More >

Paul H. Chung¹, Oussama M. Darwish¹, Claus G. Roehrborn¹, Payal Kapur², Yair Lotan¹

Canadian Journal of Urology, Vol.22, No.1, pp. 7656-7660, 2015

Abstract Introduction:We evaluated the risk of histologic upgrading and upstaging in patients who met strict active surveillance (AS) criteria on saturation biopsy and elected to undergo radical prostatectomy.
Materials and methods:A retrospective review was conducted of 362 consecutive, individual patients who underwent transrectal ultrasound guided saturation biopsy (32 cores) between 2006 and 2013. Thirty-one patients (9%) were eligible for AS based on Hopkins criteria for very low risk (VLR): stage T1c, prostate-specific antigen (PSA) density ≤ 0.15 ng/mL², Gleason ≤ 6, ≤ 2 cores and ≤ 50% core. Twenty patients (64%) elected radical prostatectomy, 2 (7%) elected radiation treatment… More >

Chad A. Reichard, Irene Makovey, Daniel A. Shoskes

Canadian Journal of Urology, Vol.22, No.1, pp. 7623-7626, 2015

Abstract Introduction: To identify a cohort of chronic pelvic pain syndrome (CPPS) patients who considered their symptoms completely resolved and analyze their demographics, clinical phenotype, treatments and NIH-Chronic Prostatitis Symptom Index (CPSI) scores.
Materials and methods: We identified 35 CPPS patients who at the follow up, reported their symptoms completely resolved (“cured”). Demographics, UPOINT phenotypes, treatments, and CPSI scores were examined. We also compared these variables to a database of 220 previously evaluated CPPS patients.
Results: Patients ranged in age from 19 to 72 years. Median follow up was 12 months. Mean change in CPSI sub scores before and after… More >

Gregory J. Diorio¹, Daniel J. Canter^2,3

Canadian Journal of Urology, Vol.22, No.2, pp. 7763-7766, 2015

Abstract For patients with non-muscle invasive bladder cancer, cystoscopy and transurethral resection/vaporization of the bladder tumor plays an integral role in the treatment of a given patient’s bladder cancer. Although considered the current gold standard for tumor detection, traditional or white light cystoscopy has been shown to have its limitations visualizing both small papillary tumors and/or carcinoma in-situ. Current efforts have been directed to closing this gap with data demonstrating that by identifying these previously missed lesions, tumor recurrence and progression rates are reduced, thereby improving patient outcomes.
Narrow Band Imaging, which can be used during… More >

C. Lowell Parsons¹, James A. Koziol², Jeffrey G. Proctor³, Paul Zupkas¹, Sulabha Argade¹

Canadian Journal of Urology, Vol.22, No.2, pp. 7739-7744, 2015

Abstract Introduction: Interstitial cystitis (IC), sometimes referred to as IC/bladder pain syndrome, is a substantial health care problem. Once considered a rare, orphan disease, it is now believed to be relatively common. This pilot study was undertaken to determine if the combination of heparin and alkalinized lidocaine (heparin-lidocaine) was more efficacious than alkalinized lidocaine at relieving pain and urgency symptoms associated with IC and also capable of yielding higher lidocaine absorption.
Materials and methods: A single blind study was conducted on 14 IC patients with a heparin-lidocaine combination versus alkalinized lidocaine instilled intravesically. In a separate study… More >