Annie Im, Ali Amjad, Mounzer Agha, Anastasios Raptis, Jing-Zhou Hou, Rafic Farah, Seah Lim, Alison Sehgal, Kathleen A. Dorritie, Robert L. Redner, Brian McLaughlin, Yongli Shuai, Shrina Duggal, Michael Boyiadzis

Oncology Research, Vol.24, No.2, pp. 73-80, 2016, DOI:10.3727/096504016X14586627440156

Abstract Relapsed acute myeloid leukemia (AML) represents a major therapeutic challenge. Achieving complete remission (CR) with salvage chemotherapy is the first goal of therapy for relapsed AML. However, there is no standard salvage chemotherapy. The current study evaluated outcomes and prognostic factors for achievement of CR in 91 AML patients in first relapse who were treated with the mitoxantrone–etoposide combination regimen. The overall response rate (CR and CRi) was 25%. Factors that were associated with a lower rate of CR included older age, shorter duration of first CR, low hemoglobin, and low platelet count. The median… More >

D.V. Jayalakshmamma¹, Dinesh P.A.², M. Sankar³, D.V. Ch,rashekhar⁴

FDMP-Fluid Dynamics & Materials Processing, Vol.10, No.3, pp. 343-357, 2014, DOI:10.3970/fdmp.2014.010.343

Abstract We examine the motion of the two concentric immiscible liquid spheres with different viscosities in an electrically conducting fluid in the presence of transverse magnetic field. The inner sphere is assumed to move at a constant velocity. The Stoke’s equation along with the Lorentz force is considered to model the resulting fluid flow, analytical solutions being obtained by the similarity solution method in terms of modified Bessel’s functions. Streamlines related to the fluid circulation in the annulus between the two liquid spheres and inside the inner liquid sphere are presented for different combinations of the More >

Hui-Fen Guo^1,2, Bin-Gang Xu^1,3, Sheng-Yan Li¹, Chong-Wen Yu²

CMES-Computer Modeling in Engineering & Sciences, Vol.80, No.2, pp. 87-112, 2011, DOI:10.3970/cmes.2011.080.087

Abstract Three-dimensional transient simulation is presented for swirling recirculating flow in a nozzle with a slotted-tube (different grooves) and the effect of the groove number is also investigated. The numerical results on the streamline angles are validated by experimental visualization using the surface oil flow technology. In the downstream center of the injectors, the vortex breakdown experiences a transition from bubble- to spiral- breakdown as time is increased. For all cases under study, as the sizes of two recirculation zones near the injector upstream wall and the step retain almost constant, the spiral breakdown shows a More >

Dyi-Cheng¹, Syuan-Yi Syong¹

CMC-Computers, Materials & Continua, Vol.13, No.3, pp. 191-200, 2009, DOI:10.3970/cmc.2009.013.191

Abstract Finite element simulations are performed to investigate the plastic deformation behavior of Ti-6Al-4V titanium alloy during its indirect extrusion through a four-hole die. The simulations assume the die, mandrel and container to be rigid bodies and ignore the temperature change induced during the extrusion process. Under various extrusion conditions, the present numerical analysis investigates the effective stress and profile of product at the exit. The relative influences of the friction factors, the temperature of billet and the eccentricity of four-hole displacement are systematically examined. The simulations focus specifically on the effects of the friction factor, More >

Y.F. Nie¹, S. Chang¹, X.K. Fan¹

CMES-Computer Modeling in Engineering & Sciences, Vol.19, No.2, pp. 135-144, 2007, DOI:10.3970/cmes.2007.019.135

Abstract A new parallel mechanism for Node-based Seamless Finite Element Method was proposed in this paper, which possessed the following three prominent points: realizing the workload balance for the parallel processes naturally, achieving synchronization of all the schedules under complex parallel environment, and filling up the gap between pre-processing and main processing. To support the scheme, three specific solutions of the parallel mechanism were proposed in this paper, all of which achieved the highly efficient parallel seamless connection between the FEM mesh generation process and structure analysis process. Two of the three schemes, i.e. dynamic scheme More >