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  • Open Access

    ARTICLE

    Clinical and cytokine profile evaluation in Northeast Brazilian psoriasis plaque-type patients

    Pablo Ramon Gualberto Cardoso1, Emerson Vasconcelos de Andrade Lima1,2, Mariana Modesto de Andrade Lima1, Moacyr Jesus Barreto de Melo Rêgo2, Claudia Diniz Lopes Marques2, Ivan da Rocha Pitta1, Angela Luzia Branco Pinto Duarte1, Maira Galdino da Rocha Pitta1

    European Cytokine Network, Vol.27, No.1, pp. 1-5, 2016, DOI:10.1684/ecn.2016.0371

    Abstract Objective and Design: Psoriasis is a common, enigmatic, and recurrent disease. The precise etiology and pathogenesis of psoriasis are still unclear. Psoriasis has been treated as an inflammatory disorder related to an underlying Th1/Th17-dominated immune response. Interleukins are involved in the development of psoriasis lesions through Th-17-associated inflammation. Th1 and Th17 cytokines are found in skin lesions and in the peripheral blood of psoriasis patients. We sought to analyze serum levels of IL-1-β, IL-8, IL-9, IL-27, IL-29, IL-35, IFN-γ, TNF and TGF-β in patients with psoriasis and healthy control volunteers. Material: Blood samples were collected More >

  • Open Access

    ARTICLE

    Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway

    Ping Zhao*, Hai-Tao Guan, Zhi-Jun Dai, Yu-Guang Ma, Xiao-Xu Liu, Xi-Jing Wang

    Oncology Research, Vol.24, No.6, pp. 437-445, 2016, DOI:10.3727/096504016X14685034103554

    Abstract Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan (testican) 1 (SPOCK1), known as testican-1, were found to be involved in the development and progression of tumors. However, in colorectal cancer (CRC), the expression pattern of SPOCK1 and its functional role remain poorly investigated. In the present study, we explored the role of SPOCK1 in CRC. Our results demonstrated that SPOCK1 is overexpressed in CRC cell lines. SPOCK1 silencing significantly inhibited the proliferation in vitro and the tumor growth in vivo. Furthermore, SPOCK1 silencing significantly attenuated the migration/invasion by reversing the EMT process in CRC cells. Finally, knockdown More >

  • Open Access

    ARTICLE

    Selenium invoked antioxidant defense system in Azolla caroliniana plant

    Hassan AMA, EM Mostafa

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 262-269, 2016, DOI:10.32604/phyton.2016.85.262

    Abstract Plants of Azolla caroliniana were treated with different selenium concentrations (0, 1, 2, 5, 7, 10 ppm) for seven days. Selenium (Se) content in Azolla plants increased significantly with increasing Se concentrations in the culture media up to 5 ppm. This indicated that Azolla plants were a good accumulator for Se. Selenium accumulation determined changes in Azolla biomass, doubling time and relative growth rates. Treatment of Azolla plants with low concentrations of Se (1 ppm) resulted in a significant increase in biomass. This was accompanied by a reduction in hydrogen peroxide and malondialdehyde (MDA) contents; the decrease percentages… More >

  • Open Access

    ARTICLE

    Aboveground biomass and concentration of nutrients in semiarid rangeland plant species: Influence of grazing and soil moisture

    Gul B1, M Islam2, S Ahmad3, S Gul1

    Phyton-International Journal of Experimental Botany, Vol.85, pp. 94-99, 2016, DOI:10.32604/phyton.2016.85.094

    Abstract Spatial and temporal patterns of aboveground biomass and nutritive value of rangeland species with respect to the influence of grazing and soil moisture were investigated. The research was conducted during two years at the Tomagh Research Station, near Sanjawi, Ziarat District, Balochistan, Pakistan. This area is protected from grazing since 1998; however, some of the area is open for grazing. Three sites were selected for research purposes: a protected plain, a protected hilly, and an unprotected plain grazed area. Sampling was carried out during the spring, summer and autumn seasons. Results revealed that soil moisture More >

  • Open Access

    RESIDENT’S CORNER

    Symptomatic cardiac metastasis responding to pazopanib in a patient with renal cell carcinoma

    Ramin Behzadigohar, Mark A. Rosenthal, Ben Tran

    Canadian Journal of Urology, Vol.22, No.3, pp. 7824-7826, 2015

    Abstract We report a case of an 82-year-old man with renal cell carcinoma who developed a cardiac metastasis within the interventricular septum. He had been under watchful waiting for indolent metastatic renal cell carcinoma for many years before developing symptoms consistent with heart failure. At this time, a 44 mm interventricular septal mass, consistent with a cardiac metastasis, was identified as the cause of his symptoms. Pazopanib was initiated which led to both a clinical and radiological response. More >

  • Open Access

    ARTICLE

    Photoresponsive Multilayer Films of Chitosan and an Azopolymer

    Raquel Fernández*, Connie Ocando, Susana C. M. Fernandes, Arantxa Eceiza, Agnieszka Tercjak

    Journal of Renewable Materials, Vol.3, No.1, pp. 49-55, 2015, DOI:10.7569/JRM.2014.634134

    Abstract The main goal of this work was the development of photoactive multilayer fi lms. Taking into account that chitosan is a biodegradable, biocompatible, nontoxic, and antibacterial biopolymer, the fabrication of chitosanbased multilayer fi lms can be an interesting pathway to obtain biopolymer-based fi lms in which properties can be combined with a light-responsive material, such as an azobenzene-containing polymer. In particular, the layer-by-layer technique was used for the fabrication of the optically active fi lms consisting of alternating layers of chitosan and an azopolymer. The infl uence of the pH and the number of bilayers More >

  • Open Access

    ARTICLE

    A state and transition model for the eastern Monte Phytogeographycal Province in Rio Negro

    Kröpfl AI1, VA Deregibus2, GA Cecchi3

    Phyton-International Journal of Experimental Botany, Vol.84, No.2, pp. 390-396, 2015, DOI:10.32604/phyton.2015.84.390

    Abstract We developed a functional model for a shrub steppe vegetation of the eastern Monte Phytogeographical Province in Río Negro (Argentina) with six stable states and 12 transitions, based on the woody encroachment degree, characteristics of the herbaceous layer and the soil surface, and biological crust cover. Information was obtained from letters of naturalists and travelers along the region since the late eighteenth century, reports of old settlers, and our own research work. On the Monte, different functional groups can be distinguished. Our work focused on the three most conspicuous to analyze the dynamics of the… More >

  • Open Access

    ARTICLE

    Biofilter efficiency of Eichhornia crassipes in wastewater treatment of fish farming in Amazonia

    Rubim MAL1, PR Isolino Sampaio1, P Parolin2,3

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 244-251, 2015, DOI:10.32604/phyton.2015.84.244

    Abstract Fish is a very important part of the human diet in Amazonia. Near the growing cities, fish populations and individual size have decreased over the past decades. Alternatives to traditional and industrial fishing arise, including fish farming. Strategies to minimize the impact of fish farms on the environment are needed to have a regular and healthy fish supply. This is to avoid a reduction of biodiversity, a depletion of natural resources, and/or the induction of significant changes in the structure and functioning of adjacent ecosystems. Very little research has been performed on management of effluents… More >

  • Open Access

    ARTICLE

    Effects of grazing on plant species diversity and carbon partitioning in semiarid rangelands of northeastern China

    Hu FL1,2, B Liu1,3, ZM Liu1,3, YT Fang1,3, CA Busso4

    Phyton-International Journal of Experimental Botany, Vol.84, No.1, pp. 209-221, 2015, DOI:10.32604/phyton.2015.84.209

    Abstract Grasslands are one of the most widespread landscapes worldwide, covering approximately one-fifth of the world’s land surface, where grazing is a common practice. How carbon storage responds to grazing in steppes remains poorly understood. We quantified the effects of grazing on community composition and species diversity, and carbon storage in two typical grasslands of northeastern China, one in Horqin and the other one in Hulunbeier. In both grasslands, grazing did not influence plant species diversity. However, it substantially decreased aboveground carbon by 31% and 54% in Horqin and Hulunbeier, respectively. Fenced and grazing treatments showed More >

  • Open Access

    ARTICLE

    A Probabilistic Approach to Hazard Mapping Based on Computer Simulations. An Example for Lava Flows at Mount Etna

    R. Rongo1,2, D. D’Ambrosio1,2, G. Iovine2,3, F. Lucà4, V. Lupiano5, V.P.Boñgolan6, W. Spataro1,2

    CMES-Computer Modeling in Engineering & Sciences, Vol.109-110, No.2, pp. 105-130, 2015, DOI:10.3970/cmes.2015.109.105

    Abstract Determining sectors that could be affected by lava flows in volcanic areas is essential for risk mitigation purposes. Traditionally, when adopting methods based on probabilistic numerical simulations, the hazard is assessed by analysing a huge set of simulations of hypothetical events, each characterized by a distinct probability of occurrence based on statistics of historical events. If lateral or eccentric eruptions are also taken into account, simulated lava flows usually start from the nodes of regular grids of potential vents, uniformly covering the study area. In this study, an alternative approach to evaluate flow-type hazard, based More >

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