ELEONIDAS MOURA LIMA^1,2, MARIANA FERREIRA LEAL³, MARÍLIA DE ARRUDA CARDOSO SMITH³, ROMMEL RODRÍGUEZ BURBANO⁴, PAULO PIMENTEL DE ASSUMPÇÃO⁵, MARIA JOSE BELLO⁶, JUAN ANTONIO REY⁶, FRANCINALDO FERREIRA DE LIMA⁷, CACILDA CASARTELLI²

BIOCELL, Vol.32, No.3, pp. 237-243, 2008, DOI:10.32604/biocell.2008.32.237

Abstract Gastric cancer is one of the most common malignancies. DNA methylation is implicated in DNA mismatch repair genes deficiency. In the present study, we evaluated the methylation status of MLH1, MSH2, MSH6 and PMS2 in 20 diffuse- and 26 intestinal-type gastric cancer samples and 20 normal gastric mucosal of gastric cancer patients from Northern Brazil. We found that none of the nonneoplastic samples showed methylation of any gene promoter and 50% of gastric cancer samples showed at least one methylated gene promoter. Methylation frequencies of MLH1, MSH2, MSH6 and PMS2 promoter were 21.74%, 17.39%, 0% and 28.26% respectively… More >

ADELINA FERREIRA¹, MAHMOUD MEHANNA^1,2, CYNTHIA P. A. PRADO³

BIOCELL, Vol.32, No.2, pp. 185-194, 2008, DOI:10.32604/biocell.2008.32.185

Abstract The spermatogenesis of Pseudis limellum, from the Southern Pantanal, Brazil, was studied from July 1995 to May 1996, through histological sections of the testis. The cells could be differentiated as: primary spermatogonia, large cells, generally with bilobed nucleus; secondary spermatogonia, smaller cells, with darker cytoplasm, chromatin of radial form; primary and secondary spermatocytes, differentiated according to the different stages of the nucleus during the successive cells divisions. Furthermore, we observed cells in process of morphologic differentiation: rounded spermatids much smaller, with nucleus containing chromatin in compacting process and cytoplasm reduction; elongated spermatids, generally parallel organized in… More >

Tienfuan Kerh^1,2, J.S. Lai¹, D. Gunaratnam², R. Saunders²

CMES-Computer Modeling in Engineering & Sciences, Vol.26, No.1, pp. 1-12, 2008, DOI:10.3970/cmes.2008.026.001

Abstract Taiwan frequently suffers from strong ground motion, and the current building code is essentially based on two seismic zones, A and B. The design value of horizontal acceleration for zone A is 0.33g, and the value for zone B is 0.23g. To check the suitability of these values, a series of actual earthquake records are considered for evaluating peak ground acceleration (PGA) for each of the zones by using neural network models. The input parameters are magnitude, epicenter distance, and focal depth for each of the checking stations, and the peak ground acceleration is calculated… More >

Nívea Maria de Freitas¹, Ana Vitória Imbronito¹, Adriana Costa Neves², Fábio Daumas Nunes³, Francisco Emilio Pustiglioni¹, Roberto Fraga Moreira Lotufo¹

European Cytokine Network, Vol.18, No.3, pp. 142-147, 2007, DOI:10.1684/ecn.2007.0100

Abstract Generalized aggressive periodontitis (GAP) comprises a group of periodontal diseases character-ized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) genes have been associated with an increased severity of chronic periodontitis. The objective of the present study was to evaluate the association between IL-1A (-889) and TNFA (-308) gene polymorphisms and GAP. One hundred nonsmoking subjects were selected, including 30 with GAP and 70 without periodontal disease. Gene polymor-phisms were analyzed by the polymerase chain reaction-restriction fragment… More >

Nivea Maria de Freitas¹, Ana Vitória Imbronito¹, Adriana Costa Neves², Fabio Daumas Nunes³, Francisco Emilio Pustiglioni¹, Roberto Fraga Moreira Lotufo¹

European Cytokine Network, Vol.18, No.3, pp. 25-30, 2007, DOI:10.1684/ecn.2007.0100

Abstract Generalized aggressive periodontitis (AP) comprises a group of periodontal diseases characterized by the rapid destruction of periodontal tissues which affect young individuals who generally present no systemic disorders. Polymorphisms in the interleukin-1 (IL-1) and tumor necrosis factor-α (TNF-α) genes have been associated with an increased severity of chronic periodontitis. The objective of the present study was to evaluate the association between IL-1A (-889) and TNFA (-308) gene polymorphisms and AP. One hundred nonsmoking subjects were selected, including 30 with AP and 70 without periodontal disease. Gene polymorphisms were analyzed by the polymerase chain reaction-restriction fragment… More >

Mayank Mohan Agarwal, Shrawan K. Singh, Naveen C. Acharya, Uttam K. Mete, Arup K. Mandal

Canadian Journal of Urology, Vol.14, No.3, pp. 3580-3582, 2007

Abstract Advanced carcinoma prostate (CaP) commonly presents as bilateral ureteric obstruction. The management often requires androgen ablation along with temporary urinary diversion (percutaneous nephrostomy or ureteric catheterization) which is not infrequently associated with complications. Two patients of hormone-naïve CaP presented to our emergency department with oliguric renal failure due to bilateral ureteric obstruction and were treated with dialysis, ketoconazole (for androgen ablation) and corticosteroids; urinary diversion was not feasible in either at the time of presentation. Brisk diuresis occurred within 48 hours obviating the need of urinary diversion. Follow-up of these cases is presented and justification More >

M. Sánchez Negrette, M.A. Montenegro, M.S. Catuogno, W.J. Lértora, M.C. Guanziroli

BIOCELL, Vol.31, No.3, pp. 391-396, 2007, DOI:10.32604/biocell.2007.31.391

Abstract Epidemiological studies in human beings and experimental studies in laboratory animals suggest that milk and dairy products can inhibit effects on the development of some kinds of tumors. Cow milk contains sphingomyelin, butyric acid, conjugated linoleic acid, calcium, vitamin A, carotene and vitamin D. All of these components are known to inhibit the process of carcinogenesis. Our objective was to determine the effect of cow milk and water buffalo milk on the development of colon neoplasias in an experimental model of carcinogenesis in rats induced with 1,2-dimethylhydrazine (DMH). Three-month-old Wistar male rats with an average… More >

Ping’en Li¹, Xianyue Su^1,2, Youquan Yin¹

CMC-Computers, Materials & Continua, Vol.6, No.2, pp. 93-102, 2007, DOI:10.3970/cmc.2007.006.093

Abstract Based on the perturbation method, for flexural wave in cased hole in anisotropic formation, the alteration in the phase velocity caused by the differences in elastic constants between anisotropic formation of interest and a reference, or unperturbed isotropic formation is obtained. Assuming the cased hole is well bonded, the Thomson-Haskell transfer matrix method is applied to calculate the dispersion relation of flexural wave in cased hole in unperturbed isotropic formation. Both the cases of a fast and slow formation are considered where the symmetry axis of a transversely isotropic (TI) formation makes an angle with… More >

Lei Zhou, Yixing Li, Tao Xia, Shengqiu Feng, Xiaodong Chen, Zaiqing Yang

European Cytokine Network, Vol.17, No.3, pp. 189-195, 2006, DOI:10.1684/ecn.2006.0039

Abstract Resistin is a 12.5-kDa cysteine-rich protein secreted from adipose tissue and is an important factorlinking obesity with insulin resistance. Here, we investigated the effect of resistin on glucose tolerance in adulthuman hepatocytes (L-02 cells). In this study, resistin cDNA was transfected into L-02 cells, and glucoseconcentration and glucokinase activity were determined subsequently. The data indicated resistin impaired,insulin-stimulated glucose utilization, which implied liver was a target tissue of resistin. To understand itsmolecular mechanism, mRNA levels of key genes in glucose metabolism and insulin signaling pathway wereanalyzed. The results demonstrated resistin-stimulated expression of glucose-6-phosphatase (G6Pase), sterolregulatory element-binding More >

M. A. BEMVENUTI

BIOCELL, Vol.30, Suppl.S, pp. 111-118, 2006

Abstract This article has no abstract. More >