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  • Open Access

    ARTICLE

    Investigation of Tissue Thermal Damage Process with Application of Direct Sensitivity Method

    Marek Jasiński*

    Molecular & Cellular Biomechanics, Vol.10, No.3, pp. 183-199, 2013, DOI:10.3970/mcb.2013.010.183

    Abstract In the paper the numerical analysis of thermal processes proceeding in the biological tissue is presented. The tissue is subjected to the external heat flux and 2D problem is taken into account. In order to determine the influence of variations of thermophysical parameters of tissue on the value of Arrhenius injury integral the direct approach of sensitivity analysis is applied. On the basis of tissue damage fraction the thermal injury formation process is analysed. At the stage of numerical realization the boundary element method is used. In the final part of the paper the example More >

  • Open Access

    ARTICLE

    Functional Electrospun Poly (Lactic Acid) Scaffolds for Biomedical Applications: Experimental Conditions, Degradation and Biocompatibility Study

    Idalba A. Hidalgo A., Felipe Sojo, Francisco Arvelo, Marcos A. Sabino∗,‡

    Molecular & Cellular Biomechanics, Vol.10, No.2, pp. 85-105, 2013, DOI:10.3970/mcb.2013.010.085

    Abstract The electrospinning technique is a method used to produce nano and microfibers using the influence of electrostatic forces. Porous three dimensional networks of continuous and interconnected fibers as scaffolds were obtained from a poly (lactic acid) solution. The concentration of the polymeric solution, 12.5% m/w, as well as the conditions of voltage (V=11kV) and tip-metallic collector distance (H=13cm) were established to develop these scaffolds through the electrospinning process. The characteristics of the scaffolds, such as fiber diameter, sintering and the biomimetics of the characteristics of a native extra cellular matrix were verified by Scanning Electron More >

  • Open Access

    ARTICLE

    Application of Numerical Methods to Elasticity Imaging

    Benjamin Castaneda, Juvenal Ormachea, Paul Rodríguez, Kevin J. Parker§

    Molecular & Cellular Biomechanics, Vol.10, No.1, pp. 43-65, 2013, DOI:10.3970/mcb.2013.010.043

    Abstract Elasticity imaging can be understood as the intersection of the study of biomechanical properties, imaging sciences, and physics. It was mainly motivated by the fact that pathological tissue presents an increased stiffness when compared to surrounding normal tissue. In the last two decades, research on elasticity imaging has been an international and interdisciplinary pursuit aiming to map the viscoelastic properties of tissue in order to provide clinically useful information. As a result, several modalities of elasticity imaging, mostly based on ultrasound but also on magnetic resonance imaging and optical coherence tomography, have been proposed and… More >

  • Open Access

    ARTICLE

    Application of the Time-Domain Boundary Element Method to Analysis of Flow-Acoustic Interaction in a Hole-tone Feedback System with a Tailpipe

    Mikael A. Langthjem1, Masami Nakano2

    CMES-Computer Modeling in Engineering & Sciences, Vol.96, No.4, pp. 227-241, 2013, DOI:10.3970/cmes.2013.096.227

    Abstract This paper is concerned with a mathematical model of a simple axisymmetric silencer-like model, consisting of a hole-tone feedback system equipped with a tailpipe. The unstable shear layer is modeled via a discrete vortex method, based on axisymmetric vortex rings. The aeroacoustic model is based on the Powell- Howe theory of vortex sound. Boundary integrals are discretized via the boundary element method; but the tailpipe is represented by the exact (one-dimensional) solution. It is demonstrated though numerical examples that this numerical model can display lock-in of the self-sustained flow oscillations to the resonant acoustic oscillations. More >

  • Open Access

    ARTICLE

    Comparison and Performance Analysis of Multiple CPU/GPU Computing Systems – Resin Infusion Flow Modeling Application

    R.H. Haney1, R.V. Mohan2

    CMES-Computer Modeling in Engineering & Sciences, Vol.95, No.5, pp. 431-452, 2013, DOI:10.3970/cmes.2013.095.431

    Abstract The use of Graphics Processing Units (GPUs) as co-processors for single CPU/GPU computing systems has become pronounced in high performance computing research, however the solution of truly large scale computationally intensive problems require the utilization of multiple computing nodes. Multiple CPU/GPU computing systems bring new complexities to the observed performance of computationally intensive applications, the more salient of which is the cost of local CPU-GPU host and intra-nodal communication. This paper compares and analyzes the performance of a computationally intensive application represented by resin infusion flow during liquid composite molding process for the manufacture of… More >

  • Open Access

    ARTICLE

    Application of a Hybrid Mesh-free Method Based on Generalized Finite Difference (GFD) Method for Natural Frequency Analysis of Functionally Graded Nanocomposite Cylinders Reinforced by Carbon Nanotubes

    Seyed Mahmoud Hosseini 1

    CMES-Computer Modeling in Engineering & Sciences, Vol.95, No.1, pp. 1-29, 2013, DOI:10.3970/cmes.2013.095.001

    Abstract In this article, the effects of carbon nanotubes distributions on natural frequency are studied for a functionally graded nanocomposite thick hollow cylinder reinforced by single-walled carbon nanotubes using a hybrid mesh-free method. The FG nanocomposite cylinder is excited by a shock loading, which is applied on the inner surface of cylinder. The first natural frequency is obtained for various nonlinear grading patterns of distributions of the aligned carbon nanotubes. The effects of various nonlinear grading patterns on natural frequency are obtained and discussed in details. The presented hybrid mesh-free method is based on the generalized More >

  • Open Access

    ARTICLE

    Application of the MLPG Mixed Collocation Method for Solving Inverse Problems of Linear Isotropic/Anisotropic Elasticity with Simply/Multiply-Connected Domains

    Tao Zhang1,2, Leiting Dong2,3, Abdullah Alotaibi4, Satya N. Atluri2,5

    CMES-Computer Modeling in Engineering & Sciences, Vol.94, No.1, pp. 1-28, 2013, DOI:10.3970/cmes.2013.094.001

    Abstract In this paper, a novel Meshless Local Petrov-Galerkin (MLPG) Mixed Collocation Method is developed for solving the inverse Cauchy problem of linear elasticity, wherein both the tractions as well as displacements are prescribed/measured at a small portion of the boundary of an elastic body. The elastic body may be isotropic/anisotropic and simply connected or multiply-connected. In the MLPG mixed collocation method, the same meshless basis function is used to interpolate both the displacement as well as the stress fields. The nodal stresses are expressed in terms of nodal displacements by enforcing the constitutive relation between… More >

  • Open Access

    REVIEW

    Applications of the MLPG Method in Engineering & Sciences: A Review

    J. Sladek1, P. Stanak1, Z-D. Han2, V. Sladek1, S.N. Atluri2

    CMES-Computer Modeling in Engineering & Sciences, Vol.92, No.5, pp. 423-475, 2013, DOI:10.3970/cmes.2013.092.423

    Abstract A review is presented for analysis of problems in engineering & the sciences, with the use of the meshless local Petrov-Galerkin (MLPG) method. The success of the meshless methods lie in the local nature, as well as higher order continuity, of the trial function approximations, high adaptivity and a low cost to prepare input data for numerical analyses, since the creation of a finite element mesh is not required. There is a broad variety of meshless methods available today; however the focus is placed on the MLPG method, in this paper. The MLPG method is… More >

  • Open Access

    ARTICLE

    An approximately H1-optimal Petrov-Galerkin meshfree method: application to computation of scattered light for optical tomography

    N Pimprikar1, J Teresa2, D Roy1,3, R M Vasu4, K Rajan4

    CMES-Computer Modeling in Engineering & Sciences, Vol.92, No.1, pp. 33-61, 2013, DOI:10.3970/cmes.2013.092.033

    Abstract Nearly pollution-free solutions of the Helmholtz equation for k-values corresponding to visible light are demonstrated and verified through experimentally measured forward scattered intensity from an optical fiber. Numerically accurate solutions are, in particular, obtained through a novel reformulation of the H1 optimal Petrov-Galerkin weak form of the Helmholtz equation. Specifically, within a globally smooth polynomial reproducing framework, the compact and smooth test functions are so designed that their normal derivatives are zero everywhere on the local boundaries of their compact supports. This circumvents the need for a priori knowledge of the true solution on the More >

  • Open Access

    ARTICLE

    Application of Residual Correction Method on non-Fourier Heat Transfer for Sphere with Time-Dependent Boundary Condition

    Po-Jen Su1, Cha’o-Kung Chen1

    CMES-Computer Modeling in Engineering & Sciences, Vol.91, No.2, pp. 135-151, 2013, DOI:10.3970/cmes.2013.091.135

    Abstract The residual correction method is used to predict the temperature distribution of non-Fourier heat transfer with time-dependent boundary condition. The approximate solution of temperature field is obtained by the residual correction method based on the maximum principle in combination with the finite difference method, making it easier and faster to obtain upper and lower approximations of exact solutions, and even can provide clear definitions of the maximum error bounds of the approximate solutions. The proposed method is found to be an effective numerical method with satisfactory accuracy. More >

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