Rahuldev Bhalla, David Dail, Paul Kozlowski, John Corman

Canadian Journal of Urology, Vol.11, No.3, pp. 2296-2298, 2004

Abstract Perivascular Epithelial Cell (PEComa) Tumors are extremely rare. These tumors are often regarded as low grade Sarcomas and treated as such. We report a case of a 70 year old female with a history of nonspecific complaints and on routine CT scan had bilateral multiple renal masses with no other extra renal disease. The largest mass on the right was 11 cm x 7 cm x 11 cm and the left there were multiple smaller masses. She underwent a right radical nephrectomy that showed a PEComa and an adjacent renal cell carcinoma. Her contralateral kidney More >

Jacques Corcos¹, Erik Schick²

Canadian Journal of Urology, Vol.11, No.3, pp. 2278-2284, 2004

Abstract Aims of study: The main objectives of the study were to measure the prevalence of overactive bladder (OAB) with its sub-types (wet OAB, dry OAB, mixed OAB) in the Canadian population and to assess prevalence variations according to gender and age.
Methods: The prevalence of OAB in Canada was investigated via a validated, computer-assisted telephone interview (CATI) system. The interviews were conducted in two steps: an initial questionnaire evaluating if respondents suffered from OAB, followed by a detailed questionnaire completing the assessment. The final data were weighted according to the census of metropolitan areas and by gender,… More >

Saleh Binsaleh¹, Mana Al-Assiri¹, Samuel Aronson², Andrew Steinberg¹

Canadian Journal of Urology, Vol.11, No.4, pp. 2352-2353, 2004

Abstract We report a case of septic shock complicating transrectal ultrasound guided prostate biopsy despite antibiotic prophylaxis with ciprofloxacin. Patient was recently treated with the same agent for other infectious illnesses. More >

Danny M. Rabah¹, Louis R. Bégin², Abdelrahman Zahran¹, Jacques Corcos¹

Canadian Journal of Urology, Vol.11, No.4, pp. 2344-2349, 2004

Abstract Objective: To evaluate and compare histological tissue reactions of the urinary bladder to human cadaveric fascia lata (CFX) slings and synthetic mesh.
Methods: Thirty rabbits were randomized to three groups: group A (multifilament - Surgipro Mesh®) 12 animals, group B (CFX) 12 animals, and group C (surgical controls) 6 animals. A piece of Mesh or CFX was fixed in direct contact with the anterior bladder neck wall. The control group simply underwent sham bladder manipulation. The animals were sacrificed at 6- and 12-week intervals, and their bladders were collected for histological analysis.
Results: Group A showed fibrosis within… More >

Heather McDonald¹, Margaret Hux¹, Marc Brisson², Lisa Bernard¹, J. Curtis Nickel³

Canadian Journal of Urology, Vol.11, No.4, pp. 2327-2340, 2004

Abstract Objective: The Proscar Long-Term Efficacy and Safety Study (PLESS) and the Medical Therapy of Prostatic Symptoms (MTOPS) study provide new evidence regarding the benefits of finasteride in the treatment of benign prostatic hyperplasia (BPH). The objective of this study was to utilize data from the PLESS and MTOPS studies to assess the cost-utility of finasteride and finasteride in combination with doxazosin, compared to doxazosin alone in men with moderate to severe BPH symptoms.
Methods: A semi-Markov decision analytic model was constructed to estimate the clinical consequences, costs and cost-utility of doxazosin, finasteride, and combination therapy. Analyses were… More >

S. Tyldesley¹, A. Coldman², T. Pickles¹

Canadian Journal of Urology, Vol.11, No.4, pp. 2316-2321, 2004

Abstract Objective: To determine whether men who relapse after neoadjuvant androgen ablation (NAA) and high-dose radiation therapy (RT) have faster PSA doubling times (PSAdt) than those who are treated with RT alone.
Materials and methods: From a prospective database of 1880 patients treated with RT for localized prostate cancer, patients were selected for further study if they had a rising PSA profile >1 ng/ml, and were treated with either no NAA, or prolonged NAA (defined as 3-12 months NAA) with a minimum 5 years follow-up. The PSAdt was calculated from the exponential line of best fit from the… More >

S. Binsaleh^1,2, J. Corcos¹, M. M. Elhilali², S. Carrier¹

Canadian Journal of Urology, Vol.11, No.5, pp. 2411-2413, 2004

Abstract Mesenchymal tumors of the urinary bladder are rare and the majority of them are malignant. We report two cases of leiomyoma of the urinary bladder presenting with symptoms of bladder outlet obstruction. The first patient was managed with staged transurethral resections, and the second with holmium laser transurethral inoculation. The outcome was excellent in both cases. A review of the literature is also outlined. More >

Richard D. Sowery, D. Robert Siemens

Canadian Journal of Urology, Vol.11, No.5, pp. 2407-2410, 2004

Abstract Objective: To characterize tumor growth of patients managed conservatively for renal cell carcinoma.
Methods: Patients electing conservative management of radiographically determined renal cell carcinomas were referred to a surveillance database. Exclusion criteria consisted of locally advanced disease (>T2) and those with metastatic disease. Clinical follow-up included renal imaging with ultrasound or computed tomography at least every 6 months.
Results: Twenty-two patients were originally managed conservatively, two of whom subsequently underwent nephrectomy because of rapid tumor growth. Mean follow-up was 26 months. Mean tumor volume and diameter at presentation was 62.4 cc and 4.08 cm respectively. Overall tumor growth More >

Patrick P.W. Luke, Andrew R. Girvan, Mohammed Al Omar, Kenneth A. Beasley, Michael Carson

Canadian Journal of Urology, Vol.11, No.5, pp. 2396-2400, 2004

Abstract We present the initial clinical experience using a robot to perform a laparoscopic dismembered pyeloplasty at a Canadian centre. Five patients were confirmed to have ureteropelvic junction obstructions through nuclear renography, cross sectional imaging and intravenous pyelography. After performing a retrograde ureteropyelography and double J stent placement, laparoscopic dismembered pyeloplasty was performed by a single surgeon at a remote workstation using the ZeusTM Telepresence Surgery System (Intuitive Surgical‚). The mean total operative time was 225±48 minutes, anastomotic time was 71±16 minutes, and the mean time required to set-up the robot was 30±17 minutes. The estimated… More >

Jeffrey S. Montgomery¹, Brent K. Hollenbeck¹, Peter C. Fisher¹, Hedwig S. Murphy^2,4, Willie Underwood, III^1,3

Canadian Journal of Urology, Vol.11, No.5, pp. 2393-2395, 2004

Abstract Scrotal masses are common findings on genitourinary exam. The majority of these masses are benign and can be identified via history and physical exam alone. Question as to the origin of these masses merits additional evaluation that typically consists of an imaging study (e.g., ultrasound) and possibly serum tumor markers (e.g., HCG and AFP). In the end, surgical exploration may be necessary. Herein, the authors describe a rare case of benign paratesticular Schwannoma and discuss the clinical presentation and treatment of scrotal masses. More >