Hubertus Himmerich1,2, Stephany Fulda1, Jakob Linseisen3,4, Henrike Seiler3, Günther Wolfram5, Stephanie Himmerich6, Kurt Gedrich6, Thomas Pollmächer1,7
European Cytokine Network, Vol.17, No.3, pp. 196-201, 2006, DOI:10.1684/ecn.2006.0037
Abstract The cytokines tumor necrosis factor-a (TNF-α), soluble TNF receptors p55 and p75, and interleukin
6 (IL-6) are involved in host defense against several microbiological agents, in the process of inflammation and
also in body weight regulation. In the present study, we sought to assess the influence of age, gender, smoking, and
body mass index on plasma levels of TNF-α, TNF receptors, and IL-6 in more than 550 adult subjects randomly
selected from the Bavarian population. None of the cytokine parameters had a normal distribution and all
distributions were significantly skewed. The cytokine plasma levels investigated More >