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  • Open Access

    ARTICLE

    Intelligent Multiclass Skin Cancer Detection Using Convolution Neural Networks

    Reham Alabduljabbar*, Hala Alshamlan

    CMC-Computers, Materials & Continua, Vol.69, No.1, pp. 831-847, 2021, DOI:10.32604/cmc.2021.018402 - 04 June 2021

    Abstract The worldwide mortality rate due to cancer is second only to cardiovascular diseases. The discovery of image processing, latest artificial intelligence techniques, and upcoming algorithms can be used to effectively diagnose and prognose cancer faster and reduce the mortality rate. Efficiently applying these latest techniques has increased the survival chances during recent years. The research community is making significant continuous progress in developing automated tools to assist dermatologists in decision making. The datasets used for the experimentation and analysis are ISBI 2016, ISBI 2017, and HAM 10000. In this work pertained models are used to… More >

  • Open Access

    ARTICLE

    Multi-Level Fusion in Ultrasound for Cancer Detection Based on Uniform LBP Features

    Diyar Qader Zeebaree1, Adnan Mohsin Abdulazeez2, Dilovan Asaad Zebari3,*, Habibollah Haron4, Haza Nuzly Abdull Hamed4

    CMC-Computers, Materials & Continua, Vol.66, No.3, pp. 3363-3382, 2021, DOI:10.32604/cmc.2021.013314 - 28 December 2020

    Abstract Collective improvement in the acceptable or desirable accuracy level of breast cancer image-related pattern recognition using various schemes remains challenging. Despite the combination of multiple schemes to achieve superior ultrasound image pattern recognition by reducing the speckle noise, an enhanced technique is not achieved. The purpose of this study is to introduce a features-based fusion scheme based on enhancement uniform-Local Binary Pattern (LBP) and filtered noise reduction. To surmount the above limitations and achieve the aim of the study, a new descriptor that enhances the LBP features based on the new threshold has been proposed.… More >

  • Open Access

    ARTICLE

    Prospective evaluation of the value of dynamic contrast enhanced (DCE) imaging for prostate cancer detection, with pathology correlation

    Ishaq Al Salmi1, Terence Menezes1, Mohamed EL-Khodary1, Sandra Monteiro2, Ehsan A. Haider1, Abdullah Alabousi1

    Canadian Journal of Urology, Vol.27, No.3, pp. 10220-10227, 2020

    Abstract Introduction: The aim of this study was to evaluate the value of dynamic contrast enhanced (DCE) imaging in multi-parametric prostate MRI (mpMRI) for the detection and staging of prostate cancer in comparison with T2W and DWI images alone in biparametric MRI (bpMRI) in treatment-naïve patients.
    Materials and methods: One hundred consecutive patients who underwent a prostate MRI at our institution from June-August 2017, as well as a systematic ultrasound-guided prostate biopsy or prostatectomy, were included. Strictly following PI-RADS v2, the MRI studies were independently interpreted by a body radiologist and a body-imaging fellow on two different occasions… More >

  • Open Access

    ARTICLE

    Two Stage Classification with CNN for Colorectal Cancer Detection

    Pallabi Sharma1,*, Kangkana Bora2, Kunio Kasugai3, Bunil Kumar Balabantaray1

    Oncologie, Vol.22, No.3, pp. 129-145, 2020, DOI:10.32604/oncologie.2020.013870

    Abstract In this paper, we address a current problem in medical image processing, the detection of colorectal cancer from colonoscopy videos. According to worldwide cancer statistics, colorectal cancer is one of the most common cancers. The process of screening and the removal of pre-cancerous cells from the large intestine is a crucial task to date. The traditional manual process is dependent on the expertise of the medical practitioner. In this paper, a two-stage classification is proposed to detect colorectal cancer. In the first stage, frames of colonoscopy video are extracted and are rated as significant if More >

  • Open Access

    ARTICLE

    Prostate cancer detection following diagnosis of atypical small acinar proliferation

    Kyle J. Ericson1, Hannah C. Wenger2, Alexandre M. Rosen3, Kyle J. Kiriluk4, Glenn S. Gerber5, Gladell P. Paner6, Scott E. Eggener5

    Canadian Journal of Urology, Vol.24, No.2, pp. 8714-8720, 2017

    Abstract Introduction: To report the incidence and characteristics of cancer following a diagnosis of atypical small acinar proliferation (ASAP) and comment on current clinical practice recommendations.
    Materials and methods: We reviewed patients that underwent prostate biopsy between 2008 and 2013 at a single institution. Men with ASAP without previous cancer were included. Clinicopathologic features including prostate-specific antigen (PSA), presence of ASAP or cancer, tumor volume, number of involved cores, and Gleason score were analyzed in men that received a repeat prostate biopsy.
    Results: Of 1450 men, ASAP was found in 75 (5%) patients. Repeat biopsy was performed in 49… More >

  • Open Access

    ARTICLE

    Prostate cancer detection rate at repeat saturation biopsy: PCPT risk calculator versus PCA3 score versus case-finding protocol

    Pietro Pepe, Francesco Aragona

    Canadian Journal of Urology, Vol.20, No.1, pp. 6620-6624, 2013

    Abstract Introduction: To evaluate Prostate Cancer Prevention Trial (PCPT) risk calculator versus prostate cancer gene 3 (PCA3) score versus case-finding protocol accuracy in prostate cancer diagnosis in patients with prostate-specific antigen (PSA) below 10 ng/mL submitted to repeat saturation biopsy (SPBx).
    Materials and methods: From December 2010 to December 2011, 100 patients (median 66 years) underwent a SPBx (median 30 cores); the indications for repeat biopsy were those of a case-finding protocol: PSA values between 4.1 ng/mL-10 ng/mL or 2.6 ng/mL-4 ng/mL with F/T PSA ≤ 25% and ≤ 20%, respectively. All patients had negative digital rectal examination… More >

  • Open Access

    ARTICLE

    The cost-effectiveness of blue light cystoscopy in bladder cancer detection: United States projections based on clinical data showing 4.5 years of follow up after a single hexaminolevulinate hydrochloride instillation

    Susan S. Garfield1, Meghan B. Gavaghan1, Shannon O. Armstrong1, J. Stephen Jones2

    Canadian Journal of Urology, Vol.20, No.2, pp. 6682-6689, 2013

    Abstract Introduction: Several studies, including the recently published phase III study by Stenzl and colleagues, have demonstrated that hexaminolevulinate hydrochloride, when used with blue light fluorescence cystoscopy, improves detection of non-muscle invasive bladder tumors compared to white light cystoscopy and transurethral resection of bladder tumors (TURB) alone.
    Materials and methods: The objective of this study was to conduct a detailed assessment of the cost-effectiveness of using hexaminolevulinate hydrochloride with blue light cystoscopy as an adjunct to white light versus white light cystoscopy alone at the time of initial TURB in the United States. A probabilistic decision tree model, More >

  • Open Access

    ARTICLE

    Length of prostate biopsy cores: does it impact cancer detection?

    Pierre Olivier Fiset1, Armen Aprikian2, Fadi Brimo1

    Canadian Journal of Urology, Vol.20, No.4, pp. 6848-6853, 2013

    Abstract Introduction: The detection of prostate carcinoma relies on adequate sampling. We aimed to evaluate whether core length is a significant biopsy parameter in the detection of cancer, especially in the low risk cancer category group.
    Materials and methods: We retrospectively analyzed pathology reports of 197 patients (2196 biopsy cores) undergoing initial transrectal ultrasound-guided biopsy. A multivariate analysis of age, total prostate-specific antigen (PSA) concentration, prostate gland volume, total number of cores, and length of biopsy cores was performed. Secondary analyses included stratification by Gleason score. Single core analysis was done to calculate a workable cut-off value for… More >

  • Open Access

    ARTICLE

    Prostate-specifi c antigen tests and prostate cancer screening: an update for primary care physicians

    John S. Kell

    Canadian Journal of Urology, Vol.17, Suppl.1, pp. 18-25, 2010

    Abstract Prostate cancer is a highly prevalent malignancy. Using serum prostatic-specifi c antigen (PSA) levels to screen for prostate cancer has led to a greater detection of this cancer, at earlier stages. However, screening for prostate cancer by determining PSA levels remains controversial. Concerns include the risk of overdiagnosis and conversely, the failure to detect all prostate cancers. This article, aimed at primary care practitioners, reviews the characteristics of an ideal screening test, in relation to the characteristics of the PSA test. It then discusses the implications of recent fi ndings from two large, randomized, prospective More >

  • Open Access

    ARTICLE

    A comparative study of prostate cancer detection and management in China and in France

    Michaël Peyromaure1,2, Kaili Mao1,2, Yinghao Sun2,3, Shujie Xia4, Nin Jiang5, Shiqing Zhang6, Gongxian Wang7, Zhongmin Liu2, Bernard Debré1,2

    Canadian Journal of Urology, Vol.16, No.1, pp. 4472-4477, 2009

    Abstract Objective: To compare the detection and management of prostate cancer in one French and six Chinese urological institutions.
    Patients and methods: All the patients subjected to prostate biopsy for suspected prostate cancer in six Chinese urological institutions and in the department of urology of the Cochin hospital, France, between January 2003 and December 2005 were included. The characteristics of patients and tumors, and the management of prostate cancer were then analyzed.
    Results: In the Chinese institutions, 95.8% of patients undergoing prostate biopsy presented with urinary disorders. The rate of abnormal digital rectal examination (DRE) ranged from 29.2% to… More >

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