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  • Open Access

    ARTICLE

    Testosterone replacement therapy for the primary care physician

    Richard W. Casey1, Jack Barkin2

    Canadian Journal of Urology, Vol.15, Suppl.4, pp. 71-77, 2008

    Abstract Testosterone replacement therapy (TRT) can have signifi cant benefi cial effects in the appropriate hypogonadal male patient. Testosterone defi ciency is common in primary care practice and recognition of the signs and symptoms of this abnormality will allow physicians to choose appropriate interventions. The symptoms of clinical hypogonadism include muscle weakness, fatigue, mood changes and a reduced libido. Signs include a reduced muscle mass, osteoporosis, anemia and increased adiposity.
    While routine screening for testosterone defi ciency, determination of testosterone levels in high risk populations, including obesity and diabetes, will help the clinician direct TRT to More >

  • Open Access

    ARTICLE

    Erectile function following unilateral cavernosal nerve replacement

    Gregory R. Hanson, Lester S. Borden, Jr., Doug D. Backous, Stephen W. Bayles, John M. Corman

    Canadian Journal of Urology, Vol.15, No.2, pp. 3990-3993, 2008

    Abstract Introduction: With nerve-sparing techniques, patients undergoing a radical prostatectomy may avoid the morbidity of erectile dysfunction. Certain patients who are not candidates for nerve-sparing procedures may be eligible for nerve interposition grafts. While bilateral cavernosal nerve grafting after radical prostatectomy has shown efficacy, the effect of unilateral nerve grafting following prostatectomy remains unclear. We evaluate a large group of patients who underwent a unilateral cavernosal nerve replacement.
    Methods: Forty patients underwent unilateral nerve sparing surgery with concomitant contralateral cavernosal nerve replacement. Patients were selected for this procedure based upon preoperative nomogram risk assessment, endorectal MRI evidence… More >

  • Open Access

    ARTICLE

    An Assumed Strain Solid Shell Element Formulation with Transversely Quadratic Displacement

    K. Lee1 and S.W. Lee 2

    CMES-Computer Modeling in Engineering & Sciences, Vol.34, No.3, pp. 253-272, 2008, DOI:10.3970/cmes.2008.034.253

    Abstract A geometrically nonlinear assumed strain formulation is used to develop a nine-node solid shell element with quadratic displacement through the thickness. The transversely quadratic element allows direct use of the constitutive equations developed for three-dimensional solids, which is convenient when material nonlinearity is involved. The nodal degrees of freedom associated with the quadratic terms in the assumed displacement through the thickness are statically condensed out at the element level. The results of numerical tests conducted on selected example problems demonstrate the validity and effectiveness of the present approach. For the cases involving linear elastic material, More >

  • Open Access

    ARTICLE

    Evaluation of Explicit-form Fundamental Solutions for Displacements and Stresses in 3D Anisotropic Elastic Solids

    Y. C. Shiah1, C. L. Tan2, V.G. Lee3

    CMES-Computer Modeling in Engineering & Sciences, Vol.34, No.3, pp. 205-226, 2008, DOI:10.3970/cmes.2008.034.205

    Abstract The main impediment to the development of efficient algorithms for the stress analysis of 3D generally anisotropic elastic solids using the boundary element method (BEM) and the local boundary integral equation (LBIE) meshless method over the years is the complexity of the fundamental solutions and the computational burden to evaluate them. The ability to analytically simplify and reduce them into as explicit a form as possible so that they can be directly computed will offer significant cost savings. In addition, they facilitate easy implementation using existing numerical algorithms with the above-mentioned methods that have been More >

  • Open Access

    ARTICLE

    Dynamic Nonlinear Material Behaviour of Thin Shells in Finite Displacements and Rotations

    C.E. Majorana1, V.A. Salomoni

    CMES-Computer Modeling in Engineering & Sciences, Vol.33, No.1, pp. 49-84, 2008, DOI:10.3970/cmes.2008.033.049

    Abstract A dynamic analysis of a thin shell finite element undergoing large displacements and rotations is here presented. The constitutive model adopted derives from the coupling of an hyperelastic basic model fulfilling a De Saint Venant-Kirchhoff criterion with a scalar damage function depending on the maximum value of a suitable strain measure attained through the deformation history; then plastic effects are included using an isotropic/kinematic hardening law. A conservative time integration scheme for the non-linear dynamics of the hyperelastic damaged-plastic thin shell is applied. The main characteristic of the scheme is to be conservative, since it More >

  • Open Access

    ARTICLE

    Finite Rotation Geometrically Exact Four-Node Solid-Shell Element with Seven Displacement Degrees of Freedom

    G. M. Kulikov1, S. V. Plotnikova1

    CMES-Computer Modeling in Engineering & Sciences, Vol.28, No.1, pp. 15-38, 2008, DOI:10.3970/cmes.2008.028.015

    Abstract This paper presents a robust non-linear geometrically exact four-node solid-shell element based on the first-order seven-parameter equivalent single-layer theory, which permits us to utilize the 3D constitutive equations. The term "geometrically exact" reflects the fact that geometry of the reference surface is described by analytically given functions and displacement vectors are resolved in the reference surface frame. As fundamental shell unknowns six displacements of the outer surfaces and a transverse displacement of the midsurface are chosen. Such choice of displacements gives the possibility to derive strain-displacement relationships, which are invariant under arbitrarily large rigid-body shell More >

  • Open Access

    ARTICLE

    Cracking and Creep Role in Displacements at Constant Load: Concrete Solids in Compression

    E. Ferretti1, A. Di Leo1

    CMC-Computers, Materials & Continua, Vol.7, No.2, pp. 59-80, 2008, DOI:10.3970/cmc.2008.007.059

    Abstract The main assumption on the basis of the identifying model of the effective law, developed by the Author, is the impossibility of considering the specimen as a continuum, when an identifying procedure from load-displacement to stress-strain in uniaxial compression is attempted. Actually, a failure mechanism with propagation of a macro-crack was found to activate from the very beginning of the uniaxial compression test forth. This leads to considering the acquired displacements as composed by two quotes: one constitutive, due to the material strain, and one of crack opening. Since the ratio between these two quotes… More >

  • Open Access

    ARTICLE

    Androgen deficiency in the aging male: a guide to diagnosis and testosterone replacement therapy

    Mathew C. Raynor1, Culley C. Carson2, Matthew D. Pearson2, Jeffrey W. Nix2

    Canadian Journal of Urology, Vol.14, Suppl.6, pp. 63-68, 2007

    Abstract A steady decline in androgen levels occurs in males as they age. Evidence suggests that this decline may be at least partially responsible for a variety of physical and mental changes associated with the aging process. For instance, abnormally low levels of androgens can lead to profound changes in bone density, body composition, as well as sexual and cognitive function. Testosterone replacement has been shown to produce improvements in many of these areas. However, this practice is not without risks, both proven and theoretic. Also, the diagnosis of androgen deficiency and the decision to treat More >

  • Open Access

    ABSTRACT

    General Corotational Rate Tensor and Replacement to Corotational Derivative of Yield Function

    K. Hashiguchi1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.4, No.4, pp. 257-264, 2007, DOI:10.3970/icces.2007.004.257

    Abstract General corotational rate of tensors in arbitrary order having the objectivity is shown first, and then it is verified that the material-derivative of yield condition can be replaced generally to the corotational derivative, i.e. the consistency condition. More >

  • Open Access

    ARTICLE

    Analyzing Production-Induced Subsidence using Coupled Displacement Discontinuity and Finite Element Methods

    Shunde Yin1, Leo Rothenburg1, Maurice B. Dusseault1

    CMES-Computer Modeling in Engineering & Sciences, Vol.19, No.2, pp. 111-120, 2007, DOI:10.3970/cmes.2007.019.111

    Abstract Subsidence problem is of great importance in petroleum engineering and environmental engineering. In this paper, we firstly apply a hybrid Displacement Discontinuity-FEM modeling to this classic problem: the evaluation of subsidence over a compacting oil reservoir. We use displacement discontinuity method to account for the reservoir surrounding area, and finite element methods in the fully coupled simulation of the reservoir itself. This approach greatly reduces the number of degrees of freedom compared to an analyzing fully coupled problem using only a finite element or finite difference discretization. More >

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