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  • Open Access

    ARTICLE

    Isolation of stem cells from adult rat kidneys

    YOUSOF GHEISARI1,2, MASOUD SOLEIMANI3*, SIROUS ZEINALI2, EHSAN AREFIAN1, AMIR ATASHI1,3, MAHIN NIKOUGOFTAR ZARIF4

    BIOCELL, Vol.33, No.1, pp. 33-38, 2009, DOI:10.32604/biocell.2009.33.033

    Abstract The kidney has an inherent ability for recovery and regeneration following acute damage. However, there has been much contention as to the source of regenerating renal cells. The aim of this study was to isolate and characterize these cells. Normal rat kidneys were minced and cells were isolated with collagenase I and were cultured in an expansion medium. Adherent cells were isolated and expanded for more than 120 days in vitro. These cells had the potential of trans-lineage differentiation into neural cells, adipocytes and osteocytes. These cells also expressed Nucleostemin, Cyclin D1, Notch1 and Survivin which More >

  • Open Access

    ABSTRACT

    Measuring displacement of a bridge using multi-channel image processing techniques

    Jong-Jae Lee, Jong-Woong Park, Young-Soo Park, Hyung-Jo Jung

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.12, No.3, pp. 92-92, 2009, DOI:10.3970/icces.2009.012.092

    Abstract Measuring the displacement of a flexible bridge is difficult particularly on a long span bridge. In this study, real-time displacement measurement of a long span bridge was carried out using digital image processing techniques which require a target recognition algorithm, projection of the captured image, and calculation of the actual displacement using target geometry and the number of pixels moved. To measure the displacement of a bridge from a distant location which can be regarded as a fixed reference point, a novel image processing method has been devised. By measuring the same target with two More >

  • Open Access

    ABSTRACT

    Fracture simulation with coupling moisture diffusion effect and external loading in fiber reinforced cementitious composites

    Kunhwi Kim, Jong Min Park, John E. Bolander, Yun Mook Lim1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.12, No.1, pp. 5-6, 2009, DOI:10.3970/icces.2009.012.005

    Abstract Fiber reinforced cementitious composites (FRCC) are the most recently used materials in the civil engineering field due to their mechanical advantages over the cementitious materials. While, the durability performance of cement-based composites can affect the service life of the structural component or system. Sometimes, incompatible behaviors (e.g. thermal expansion, moisture diffusion) among components cause micro-cracking and further durability problems. Physical experimentations have generally been used for understanding the durability of cementitious composites, but increasingly computational simulations are being used to gain new insights. However, the most of existing simulation models are limited in coupling with… More >

  • Open Access

    ABSTRACT

    Piezoelectric four-node geometrically exact solid-shell element with seven displacement degrees of freedom

    S.V. Plotnikova1, M.G. Kulikov1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.11, No.2, pp. 49-52, 2009, DOI:10.3970/icces.2009.011.049

    Abstract This article has no abstract. More >

  • Open Access

    ABSTRACT

    Non-Linear geometrically exact solid-shell elements with seven displacement degrees of freedom

    G.M. Kulikov1, S.V. Plotnikova1

    The International Conference on Computational & Experimental Engineering and Sciences, Vol.10, No.1, pp. 25-26, 2009, DOI:10.3970/icces.2009.010.025

    Abstract This paper presents the robust non-linear geometrically exact four-node solid-shell elements based on the first-order seven-parameter equivalent single-layer theory, which permits us to utilize the 3D constitutive equations. The term "geometrically exact" reflects the fact that geometry of the reference surface is described by analytically given functions and displacement vectors are resolved in the reference surface frame. As fundamental shell unknowns six displacements of the outer surfaces and a transverse displacement of the midsurface are chosen. Such choice of displacements gives the possibility to derive strain-displacement relationships, which are invariant under arbitrarily large rigid-body shell… More >

  • Open Access

    REVIEW

    Molecular Basis of Force Development by Skeletal Muscles During and After Stretch

    Dilson E. Rassier*

    Molecular & Cellular Biomechanics, Vol.6, No.4, pp. 229-242, 2009, DOI:10.3970/mcb.2009.006.229

    Abstract When activated skeletal muscles are stretched at slow velocities, force increases in two phases: (i) a fast increase, and (ii) a slow increase. The transition between these phases is commonly associated with the mechanical detachment of cross-bridges from actin. This phenomenon is referred to asforce enhancement during stretch. After the stretch, force decreases and reaches steady-state at levels that are higher than the force produced at the corresponding length during purely isometric contractions. This phenomenon is referred to asresidual force enhancement.The mechanisms behind the increase in force during and after stretch are still a matter More >

  • Open Access

    ARTICLE

    Micromechanics Based Stress-Displacement Relationships of Rough Contacts: Numerical Implementation under Combined Normal and Shear Loading

    Anil Misra1, Shiping Huang1

    CMES-Computer Modeling in Engineering & Sciences, Vol.52, No.2, pp. 197-216, 2009, DOI:10.3970/cmes.2009.052.197

    Abstract The behavior of contact between solid bodies with rough surfaces under combined normal and shear loading remains a problem of interest in many areas of engineering. In this paper, we have utilized a micromechanical methodology to derive an expression of stress-displacement relationship applicable to combined normal and shear loading conditions. The micromechanical methodology considers the mechanics of asperity contacts and the interface roughness in terms of asperity height and asperity contact orientation distribution. A numerical procedure is implemented to evaluate the derived expressions under complex and mixed loading conditions using an incremental approach. We find More >

  • Open Access

    ARTICLE

    The Stress Analysis of Thin Contact Layers: a Viscoelastic Case

    C. Y. Chen1, C. Atkinson2

    CMES-Computer Modeling in Engineering & Sciences, Vol.48, No.3, pp. 219-240, 2009, DOI:10.3970/cmes.2009.048.219

    Abstract In this paper, we extend our previous analysis of a contact problem with a circular indenter pressed normally against a semi-infinite elastic composite to that of a semi-infinite viscoelastic composite which consists of a contact layer with uniform thickness welded together with another dissimilar medium. Using the correspondence principle between the Laplace transformed elastic equations and the viscoelastic ones, the asymptotic results derived previously for the pure elastic case are readily adopted for the viscoelastic one with the elastic constants replaced by appropriate functions of Laplace transformed variables for the linear viscoelastic solid. We focus More >

  • Open Access

    ARTICLE

    A Simplified Analysis of the Tire-Tread Contact Problem using Displacement Potential Based Finite-Difference Technique

    S Reaz Ahmed1, S K Deb Nath1

    CMES-Computer Modeling in Engineering & Sciences, Vol.44, No.1, pp. 35-64, 2009, DOI:10.3970/cmes.2009.044.035

    Abstract The paper presents a simplified analysis of stresses and deformations at critical sections of a tire-tread. Displacement potential formulation is used in conjunction with the finite-difference method to model the present contact problem. The solution of the problem is obtained for two limiting cases of the contact boundary - one allows the lateral slippage and the other conforms to the no-slip condition along the lateral direction. The influential effects of tire material and tread aspect-ratio are discussed. The reliability and accuracy of the solution is also discussed in light of comparison made with the usual More >

  • Open Access

    ARTICLE

    Variational formulation and Nonsmooth Optimization Algorithms in Elastostatic Contact Problems for Cracked Body

    V.V. Zozulya1

    CMES-Computer Modeling in Engineering & Sciences, Vol.42, No.3, pp. 187-216, 2009, DOI:10.3970/cmes.2009.042.187

    Abstract The mathematical statement for contact problem with unilateral restrictions and friction is done in classical and weak forms. Different variational formulation of unilateral contact problems with friction based on principles of virtual displacements and virtual stresses are considered. Especially boundary variational functionals that are used with boundary integral equations have been established. Nonsmooth optimization algorithms of Udzawa type for solution of unilateral contact problem with friction have been developed. Some theoretical results of existence and uniqueness in elastostatic unilateral contact problem with friction are outlined. More >

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