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  • Open Access

    ARTICLE

    Morphology, Phylogeny and Culture Characteristics of Ganoderma gibbosum Collected from Kunming, Yunnan Province, China

    Thatsanee Luangharn1,2,3,4, Samantha C. Karunarathna1,3, Peter E. Mortimer1,4,*, Kevin D. Hyde3,5, Jianchu Xu1,3,4,*

    Phyton-International Journal of Experimental Botany, Vol.89, No.3, pp. 743-764, 2020, DOI:10.32604/phyton.2020.09690 - 22 June 2020

    Abstract Ganoderma is a genus of medicinally and economically important mushrooms in the family Ganodermataceae. Ganoderma species are popular medicinal mushrooms and their health benefits are well-documented. Ganoderma is a cosmopolitan genus that is widely distributed in both tropical and temperate regions. This genus is characterized by its unique laccate or non-laccate species with double-walled basidiospores. Here, we report on eight collections of G. gibbosum collected during surveys in Kunming, Yunnan Province, China. The specimens are described and illustrated based on macro- and micro-morphological characteristics. Total DNA of the eight G. gibbosum strains were extracted using the Biospin Fungal More >

  • Open Access

    ARTICLE

    TTF1-NPs Induce ERS-Mediated Apoptosis and Inhibit Human Hepatoma Cell Growth In Vitro and In Vivo

    Bin Xiao*1, Chao Liu*†1, Bing-tong Liu*1, Xuan Zhang*, Rong-rong Liu*, Xue-Wu Zhang*

    Oncology Research, Vol.23, No.6, pp. 311-320, 2015, DOI:10.3727/096504016X14567549091341

    Abstract Previous studies have shown that 5,2',4'-trihydroxy-6,7,5'-trimethoxyflavone (TTF1) is the primary anticancer constituent of the traditional Chinese medicinal plant Sorbaria sorbifolia (SS), which has been applied to treat cancer in China. In this study, we investigated the in vitro and in vivo antitumor effects and biological mechanisms of small-molecule TTF1 nanoparticles (TTF1-NPs). The effects of TTF1-NPs on cell growth and apoptosis were investigated using human hepatoma cells. The molecular changes associated with the effects of TTF1-NPs were analyzed by immunocytochemistry and Western blot analysis. The in vivo effect of TTF1-NPs was investigated using the HepG2 tumor xenograft More >

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