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  • Open Access

    ARTICLE

    Defoliation management of kleingrass (Panicum coloratum L. var coloratum) cv Verde

    Ferri CM, VV Jouve, AM Sáenz

    Phyton-International Journal of Experimental Botany, Vol.86, pp. 190-198, 2017, DOI:10.32604/phyton.2017.86.190

    Abstract The defoliation frequency determines above and below ground biomass accumulation, pasture structure and nutritive value. Two defoliation experiments with Panicum coloratum were performed, from September to March. One of them was conducted in pots under greenhouse conditions, and the other one in field plots for three growing seasons (EC) at the Faculty of Agronomy, La Pampa, Argentina (36˚ 46' S; 64˚ 16' W). Defoliation frequency treatments were four cutting intervals (IC; 3, 4, 6 and 8 weeks). In greenhouse experiment, live leaf blade accumulation rates (TAL), tiller appearance (TAM) and death (TMM) rates, live leaf blade… More >

  • Open Access

    ARTICLE

    Growth induction of root and tubercle in Caladium bicolor with organic fertilizer

    González-Cervantes G1, JA Chávez-Simental2, IA Ortiz-Sánchez3, LM Valenzuela-Núñez4, MA Macías-Corral5, JG Arreola-Avila6

    Phyton-International Journal of Experimental Botany, Vol.86, pp. 40-45, 2017, DOI:10.32604/phyton.2017.86.040

    Abstract The introduction of ornamental crops to the Comarca Lagunera is a great market opportunity for producers of flowers, just as it is the case of Caladium bicolor which is exported to Europe, USA, Caribbean islands and Africa. The use of organic products derived from cattle manure for fertilization, improves physical soil conditions and provides significant amount of nutrients to plants and reduce production costs. Therefore, the objective of this study was to quantify the growth of tubercle and root of the ornamental plant Caladium bicolor by applying organic fertilizer (OF) extracted from cattle manure. The experimental design… More >

  • Open Access

    ARTICLE

    Astragaloside IV Enhances Cisplatin Chemosensitivity in Human Colorectal Cancer via Regulating NOTCH3

    Tao Xie*, Yao Li, Shi-Lei Li*, Hai-Feng Luo

    Oncology Research, Vol.24, No.6, pp. 447-453, 2016, DOI:10.3727/096504016X14685034103590

    Abstract Although astragaloside IV exhibits anti-inflammation, immunoregulatory, and anticancer properties, the chemosensitization effects of astragaloside IV in colorectal cancer have never been reported. Our study tested whether astragaloside could increase cisplatin sensitivity in colorectal cancer. CCK-8 assay was used to measure the cell viability of colorectal cancer cells. Quantitative real-time PCR and Western blot were performed to determine the mRNA and protein expression, respectively. Our data revealed that astragaloside IV administration significantly suppressed the cell growth of colorectal cancer cells, whereas no obvious cytotoxicity of astragaloside IV was observed in nonmalignant colonic cells. In addition, combined… More >

  • Open Access

    ARTICLE

    Knockdown of SPOCK1 Inhibits the Proliferation and Invasion in Colorectal Cancer Cells by Suppressing the PI3K/Akt Pathway

    Ping Zhao*, Hai-Tao Guan, Zhi-Jun Dai, Yu-Guang Ma, Xiao-Xu Liu, Xi-Jing Wang

    Oncology Research, Vol.24, No.6, pp. 437-445, 2016, DOI:10.3727/096504016X14685034103554

    Abstract Sparc/osteonectin, cwcv, and kazal-like domains proteoglycan (testican) 1 (SPOCK1), known as testican-1, were found to be involved in the development and progression of tumors. However, in colorectal cancer (CRC), the expression pattern of SPOCK1 and its functional role remain poorly investigated. In the present study, we explored the role of SPOCK1 in CRC. Our results demonstrated that SPOCK1 is overexpressed in CRC cell lines. SPOCK1 silencing significantly inhibited the proliferation in vitro and the tumor growth in vivo. Furthermore, SPOCK1 silencing significantly attenuated the migration/invasion by reversing the EMT process in CRC cells. Finally, knockdown More >

  • Open Access

    ARTICLE

    IL-17A Promotes the Migration and Invasiveness of Colorectal Cancer Cells Through NF-kB-Mediated MMP Exp

    Hongtao Ren*, Zhongwei Wang*, Shuqun Zhang*, Hongbing Ma*, Yali Wang*, Lijun Jia*, Yiming Li

    Oncology Research, Vol.23, No.5, pp. 249-256, 2015, DOI:10.3727/096504016X14562725373716

    Abstract Interleukin-17A (IL-17A) plays a significant role in many inflammatory diseases and cancers. The aim of this study is to investigate the effect of IL-17A on the invasiveness of colorectal cancer. In the study, we found that IL-17A could promote the migration and invasion of colorectal cancer cells. Furthermore, after being treated with IL-17A, the expression and activity of matrix metalloproteinase 2 (MMP-2) and MMP-9 were upregulated. Moreover, the nuclear/overall fractions and DNA-binding activity of p65 and p50 were dramatically elevated by IL-17A. Pretreatment with a nuclear factor-kB (NF-kB) inhibitor (PDTC) or PI3K/AKT inhibitor (LY294002) was More >

  • Open Access

    ARTICLE

    Thermal Radiofrequency Ablation as an Adjuvant Therapy for Patients With Colorectal Liver Metastasis

    Yaohua Fan*†1, Xiyan Zhu*1, Qiuping Lan*, Fang Lou*, Yu Zheng*, Haizhou Lou*, Yong Fang*, Wei Jin*, Hongming Pan*, Kaifeng Wang*‡

    Oncology Research, Vol.23, No.5, pp. 219-228, 2015, DOI:10.3727/096504016X14567549091260

    Abstract Radiofrequency ablation (RFA) is a minimally invasive technology for the treatment of liver malignancies and is used as an adjuvant therapy in patients with colorectal liver metastasis (CLM). This study enrolled a total of 49 CLM patients who underwent RFA treatment. Univariate and multivariate analyses were performed using the log-rank test and Cox proportional hazard model, respectively. Univariate analysis showed that OS was closely correlated with tumor size, frequency of RFA treatment, resection of the liver lesion, and CEA levels before RFA (p<0.05). Multivariate analysis revealed that resection of CLM lesions after RFA, frequency of RFA More >

  • Open Access

    ARTICLE

    Knockdown of Long Noncoding RNA GHET1 Inhibits Cell Proliferation and Invasion of Colorectal Cancer

    Jianyu Zhou*, Xiaorong Li*, Meirong Wu, Changwei Lin*, Yihang Guo*, Buning Tian*

    Oncology Research, Vol.23, No.6, pp. 303-309, 2015, DOI:10.3727/096504016X14567549091305

    Abstract Emerging evidence has identified the vital role of long noncoding RNAs (lncRNAs) in the development of colorectal cancer. In this study, we aimed to investigate the role of lncRNA gastric carcinoma highly expressed transcript 1 (GHET1) in colorectal cancer. We analyzed the expression of GHET1 in colorectal cancer (CRC) tissues by using ISH. We found that GHET1 expression was significantly increased in the CRC samples compared with adjacent tissues. Furthermore, the cancer tissues had higher GHET1 mRNA levels than their matched adjacent tissues. GHET1 expression was also significantly increased in the CRC cell lines compared More >

  • Open Access

    ARTICLE

    MicroRNA-92a Promotes Colorectal Cancer Cell Growth and Migration by Inhibiting KLF4

    Huiqing Lv*, Zhongmin Zhang, Yaoxia Wang, Chenglin Li, Weihong Gong, Xin Wang

    Oncology Research, Vol.23, No.6, pp. 283-290, 2015, DOI:10.3727/096504016X14562725373833

    Abstract Colorectal cancer (CRC) is the third most common malignancy with high mortality around the world. However, the biological mechanism of CRC carcinogenesis is not completely known. In the present study, we determined the role of miR-92a in the regulation of CRC cell motility. Expression of miR-92a is aberrantly upregulated in human CRC tissues and cultured cells, as shown by RT-PCR analysis. The effects of miR-92a on the proliferation and migration of human CRC SW620 and LoVo cells were measured by CCK-8 and Transwell assay, respectively. Results showed that the proliferation and migration capacity of both… More >

  • Open Access

    ARTICLE

    Analyzing digital color descriptors in wheat

    Salomón N1, V Misller1, C Delrieux2, R Miranda3

    Phyton-International Journal of Experimental Botany, Vol.84, No.2, pp. 306-311, 2015, DOI:10.32604/phyton.2015.84.306

    Abstract Color is one of the factors used in quality estimation in many agricultural and food products. Currently, the evaluation of color depends on judgments made by human experts. These are subjective and inevitably affected by physical, physiological and environmental conditions. Suitable instrumental is required to provide objectivity and coherence to color measurements and quantitative expressions. It would be very useful to have tools that allow both practical and precise approaches to chromatic evaluation of products for human consumption. This work suggests a methodology which might contribute to solve that constraint and the analysis of environmental… More >

  • Open Access

    ARTICLE

    Germination and vigour of Crotalaria juncea L. (Fabaceae) seed morphotypes

    Pascualides AL y NS Ateca

    Phyton-International Journal of Experimental Botany, Vol.82, pp. 313-319, 2013, DOI:10.32604/phyton.2013.82.313

    Abstract Crotalaria juncea L. (Fabaceae) is an annual herbaceous species native to India. Their seeds have polymorphism in the seed coat color and different seed sizes. Seeds were grouped according to their seed coat color into uniform (dark gray seeds) and variegated (brown mottled seeds), to evaluate the vigour of C. juncea seed morphotypes. They were also classified into small (< 5mm length) and big seeds (>5 mm length). The 1000 seed weight, germination percentage, length and seedling dry weight, electrical conductivity and field emergence were evaluated. The results showed that uniform seeds had greater weight than those… More >

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