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  • Open Access

    ARTICLE

    Cytokine profiles in peripheral, placental and cord blood in pregnant women from an area endemic for Plasmodium falciparum

    Marielle K. Bouyou-Akotet1,2,3, Maryvonne Kombila3, Peter G. Kremsner1,2, Elie Mavoungou1,2

    European Cytokine Network, Vol.15, No.2, pp. 120-125, 2004

    Abstract During gestation, inflammatory cytokines are sometimes more abundant than growth-promoting cytokines, and via direct or indirect effects, proinflammatory cytokines lead to intrauterine growth retardation. We used an enzyme-linked immunosorbent assay to measure the concentrations of three proinflammatory cytokines, tumor necrosis factor alpha (TNF-α), interleukin-12 (IL-12p40), as well as interleukin-15 (IL-15) and monocyte chemotactic protein-1 (MCP-1), in plasma from peripheral, placental and cord blood of thirty pregnant Gabonese women. All of these women lived in Libreville and Lambaréné, two malaria hyperendemic areas. IL-12p40 concentrations were higher in cord blood than in placental or peripheral blood. The… More >

  • Open Access

    RESIDENT’S CORNER

    Long-term penile incarceration by a metal ring resulting in urethral erosion and chronic lymphedema

    Richard D. Sowery, Darren T. Beiko, Jeremy P. W. Heaton

    Canadian Journal of Urology, Vol.11, No.1, pp. 2167-2168, 2004

    Abstract A patient presented with a metal ring around the base of his penis. The ring had been placed 3 years prior to presentation. Intra-operative findings revealed a ventral erosion with complete transection of the urethra and massive fixed lymphedema of the penile skin distal to the ring. Treatment consisted of removal of the ring with metal shears and bolt cutters. Small reduction of the edema was seen 3 months following removal, and the patient refused further treatment. The most interesting part of the outcome was the preservation of penile urethral voiding although intromission was not More >

  • Open Access

    RESIDENT’S CORNER

    Wilms' Tumor at the Children’s Hospital of Eastern Ontario: 1990-2001

    Michael L. Pianezza1, Steven Rubin2, Juan Bass2, Shirley Chou2, John G. Pike1, Michael P. Leonard1

    Canadian Journal of Urology, Vol.11, No.1, pp. 2151-2156, 2004

    Abstract Background: Wilms' Tumor is the most common malignant neoplasm of the urinary tract in children. Since 1969, the National Wilms' Tumor Study Group (NWTSG) has contributed to improving the clinical management and outcome of children affected by Wilms' Tumor. We have managed our patients according to NWTSG protocols and report our results herein.
    Methods: Retrospective chart review of consecutive patients presenting at the Children's Hospital of Eastern Ontario (CHEO) with a diagnosis of Wilms' Tumor between April 1990 and March 2001.
    Results: Forty patients with Wilms' Tumor (18 M/22 F) were diagnosed at CHEO during this interval. Mean… More >

  • Open Access

    ARTICLE

    Prevalence of overactive bladder and incontinence in Canada

    Jacques Corcos1, Erik Schick2

    Canadian Journal of Urology, Vol.11, No.3, pp. 2278-2284, 2004

    Abstract Aims of study: The main objectives of the study were to measure the prevalence of overactive bladder (OAB) with its sub-types (wet OAB, dry OAB, mixed OAB) in the Canadian population and to assess prevalence variations according to gender and age.
    Methods: The prevalence of OAB in Canada was investigated via a validated, computer-assisted telephone interview (CATI) system. The interviews were conducted in two steps: an initial questionnaire evaluating if respondents suffered from OAB, followed by a detailed questionnaire completing the assessment. The final data were weighted according to the census of metropolitan areas and by gender,… More >

  • Open Access

    ARTICLE

    Edematogenic and myotoxic activities of the duvernoy’s gland secretion of Philodryas olfersii from the north-east region of Argentina

    OFELIA ACOSTA DE PÉREZ1, LAURA LEIVA DE VILA2, MARÍA ELISA PEICHOTO2, SILVANA MARUÑAK3, RAQUEL RUÍZ3, PAMELA TEIBLER3, CAROLINA GAY2, LAURA REY4

    BIOCELL, Vol.27, No.3, pp. 363-370, 2003, DOI:10.32604/biocell.2003.27.363

    Abstract Philodryas olfersii is found in South America, from Amazonas to Patagonia. It is important to characterize the venom of P. olfersii, who inhabits the North-East region of Argentina, since snake venoms are known to exhibit considerable variability in composition and biological activities. In this work, mice weighing 18-20 g (n = 4 for each experimental group) were used. For the edematogenic activity mice were injected s.c. in the right foot pad with 50 µl of solutions containing different amounts of venom, whereas the left foot pad was injected with 50 µl of PBS. Two hours after injection mice… More >

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