Yaohong Liu, Wensou Huang, Mingji He, Hui Lian, Yongjian Guo, Jingjun Huang, Jingwen Zhou, Kangshun Zhu

Oncology Research, Vol.27, No.5, pp. 565-573, 2019, DOI:10.3727/096504018X15313896322888

Abstract This study aimed to investigate the efficacy and safety of drug-eluting beads transarterial chemoembolization (DEB-TACE) treatment in Barcelona Clinic Liver Cancer (BCLC) stage C liver cancer patients. In 39 patients with BCLC stage C liver cancer, after the first cycle of DEB-TACE, 2 (5.1%) and 24 (61.5%) patients achieved complete response (CR) and partial response (PR) to give an overall objective response rate (ORR) of 66.7%. With respect to the second cycle of therapy, the ORR was higher in patients receiving DEB-TACE compared with those receiving cTACE (57.1% vs. 11.1%). After the first cycle of… More >

Jason F. Goldberg¹, Craig L. Jensen², Rajesh Krishnamurthy³, Nidhy P. Varghese⁴, Henri Justino¹

Congenital Heart Disease, Vol.13, No.1, pp. 124-130, 2018, DOI:10.1111/chd.12537

Abstract Objective: We describe the long-term follow-up of a child with recurrent hemoptysis due to severe pulmonary vein stenosis decompressing via collaterals to esophageal varices.
Design: Case report
Setting: Tertiary children’s hospital
Patient: Single child through ages 2- to 11-year old
Interventions: The child underwent cutting balloon angioplasty, bare metal stenting, and implantation of a PTFE-covered stent, all of which failed rapidly. Only after placement of a paclitaxel drug eluting stent did he have prolonged relief from hemoptysis and long-term patency of the treated vein. The stents were serially dilated to keep up with somatic growth of the child, eventually culminating More >

Neal Shore¹, Sheldon Freedman², Steven Gange³, William Moseley⁴, Sean Heron⁵, Ron Tutrone⁶, Thomas Brown⁷, Jack Barkin⁸

Canadian Journal of Urology, Vol.21, No.1, pp. 7094-7101, 2014

Abstract Introduction: The prostatic urethral Lift (PUL) procedure offers a novel treatment for men with lower urinary tract obstructive symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH). Most patients who seek LUTS/BPH treatment choose the intervention that offers the expectations of a significant improvement in quality of life and the least chance of short or long term morbidity. We report the results of a prospective, non-randomized study designed to further characterize the perioperative subject experience with the PUL procedure.
Materials and methods: The PUL procedure employs permanent implants to mechanically pull the prostatic lateral lobes apart. Subjects… More >

Thomas Werner^1,2, Susan M. Dombrowski^3,4, Carlos Zgheib⁵, Fouad A. Zouein⁵, Henry L. Keen⁶, Mazen Kurdi^5,7, George W. Booz⁵

European Cytokine Network, Vol.24, No.2, pp. 75-90, 2013, DOI:10.1684/ecn.2013.0336

Abstract Microarrays do not yield direct evidence for functional connections between genes. However, transcription factors (TFs) and their binding sites (TFBSs) in promoters are important for inducing and coordinating changes in RNA levels, and thus represent the first layer of functional interaction. Similar to genes, TFs act only in context, which is why a TF/TFBS-based promoter analysis of genes needs to be done in the form of gene(TF)-gene networks, not individual TFs or TFBSs. In addition, integration of the literature and various databases (e.g. GO, MeSH, etc) allows the adding of genes relevant for the functional… More >

Nessa Johnson, John Abraham^*, Zach Helgeson, Michael Hennessey

Frontiers in Heat and Mass Transfer, Vol.2, No.2, pp. 1-7, 2011, DOI:10.5098/hmt.v2.2.3006

Abstract A numerical simulation has been performed on the hemodynamics associated with embolization procedures. The flow geometry includes a multibranch artery which is upstream of a targeted tumor. During the procedure, drug-eluting particles are released into the local arterial geometry and are carried downstream by the flowing blood. The intention is to cause embolization of a daughter artery which feeds the tumor. As particles are injected into the blood stream, and as the embolization progresses, it is possible for the particulates to substantially alter the blood flow in the main artery. This alteration may lead to… More >

Sacristán M, AM Millanes, B Fontaniella, ME Legaz, C Vicente

Phyton-International Journal of Experimental Botany, Vol.77, pp. 253-262, 2008, DOI:10.32604/phyton.2008.77.253

Abstract Secreted arginases from Evernia prunastri and Xanthoria parietina thalli, exhibiting lectin activity, have been purified to homogeneity. Analyses of both amino acid and glycoside composition are reported. Purified proteins have been subjected to tryptic digestion and some amino acid sequences have been analyzed. An undecapeptide from Evernia arginase, which shows some degree of homology with the domain to which Mn²⁺ binds, a heptapeptide and an undecapeptide from Xanthoria arginase have been analyzed, and homologies with some arginases from other fungi and plants have been found. More >

P. CORNEJO*, E.L. CAMADRO**, R.W. MASUELLI*

BIOCELL, Vol.30, No.3, pp. 413-421, 2006, DOI:10.32604/biocell.2006.30.413

Abstract The Endosperm Balance Number (EBN) is an important concept for potato breeding and has evolutionary importance in tuber-bearing Solanum species. The EBN is part of the post-zygotic hybridization barriers in the group and represents a reproductive isolating mechanism. Few genes have been proposed to be involved in its genetic control; until now, however, neither specific genes nor its molecular basis have been well established. Histological observations of embryo and endosperm development in inter-EBN crosses in tuber-bearing Solanum revealed phenotypes similar to those recently described in Arabidopsis seed mutants. The common feature between them is that the endosperm… More >