Jihan Kim¹, Yong Hyup Kim¹, Sung Won Lee²

CMES-Computer Modeling in Engineering & Sciences, Vol.6, No.3, pp. 263-276, 2004, DOI:10.3970/cmes.2004.006.263

Abstract The Koiter's asymptotic method is combined with the assumed strain solid shell element formulation for postbuckling analysis of composite and sandwich structures. The assumed strain solid shell element is free of locking and the small angle assumption, and it allows multiple plies through the element thickness. While laminated composite structures are modeled with single element through the thickness, sandwich structures are modeled with three elements stacked through the thickness to model the face sheets and the core independently. The Koiter's method is used to trace initial postbuckling path. Subsequently, the Koiter's method is switched to More >

L. G. Zhou¹, L. M. Hsiung², Hanchen Huang¹

CMES-Computer Modeling in Engineering & Sciences, Vol.6, No.3, pp. 245-252, 2004, DOI:10.3970/cmes.2004.006.245

Abstract Using molecular dynamics simulations, we study the deformation of polysynthetically twinned (PST) TiAl at room temperature. The simulation cell is pre-strained and thermodynamically relaxed to zero stress, so that no dislocations pre-exist in γ−α₂ interfaces. A uniaxial compression is then applied along one 1/6<112] direction. Our results show that interfacial dislocation pairs nucleate at the γ−α₂ interface under the compression. The glide and agglomeration of these dislocations lead to the nucleation of deformation twins from the interface. Based on our studies, twins may nucleate without pre-existing interfacial dislocations. Further we have monitored the propagation of the More >

B. Wang¹, H.Q. Zhang¹, C.K. Chan², X.L. Wang¹

CMC-Computers, Materials & Continua, Vol.1, No.3, pp. 275-288, 2004, DOI:10.3970/cmc.2004.001.275

Abstract Dilute gas-particle turbulent flow over a backward-facing step is numerically simulated. Large Eddy Simulation (LES) is used for the continuous phase and a Lagrangian trajectory method is adopted for the particle phase. Four typical locations in the flow field are chosen to investigate the two-phase velocity fluctuations. Time-series velocities of the gas phase with particles of different sizes are obtained. Velocity of the small particles is found to be similar to that of the gas phase, while high frequency noise exists in the velocity of the large particles. While the mean and rms velocities of More >

L. Chernin¹, K.Y. Volokh^1,2

CMC-Computers, Materials & Continua, Vol.1, No.3, pp. 259-274, 2004, DOI:10.3970/cmc.2004.001.259

Abstract The conventional approach to analysis of thin film delamination is based on the consideration of the film, which is subjected to residual stresses arising from the thermal mismatch between the film and the substrate, within the framework of the classical fracture mechanics and the structural buckling theories. Such concepts as the energy release rate and the stress intensity factors are crucial in this case.

A different approach to analysis of thin film delamination considers the effect of the compliant interface between the film and the substrate. This compliant interface is described by the traction-separation… More >

T. Tsangaris¹, Y.–S. Smyrlis^{1, 2}, A. Karageorghis^{1, 2}

CMC-Computers, Materials & Continua, Vol.1, No.3, pp. 245-258, 2004, DOI:10.3970/cmc.2004.001.245

Abstract The Method of Fundamental Solutions (MFS) is a boundary-type method for the solution of certain elliptic boundary value problems. In this work, we develop an efficient matrix decomposition MFS algorithm for the solution of biharmonic problems in annular domains. The circulant structure of the matrices involved in the MFS discretization is exploited by using Fast Fourier Transforms. The algorithm is tested numerically on several examples. More >

R. Gangadharan¹, A. Rajagopal¹, S.M. Sivakumar^{1, 2}

CMC-Computers, Materials & Continua, Vol.1, No.3, pp. 229-244, 2004, DOI:10.3970/cmc.2004.001.229

Abstract A new r-h adaptive scheme is proposed and formulated. It involves a combination of the configurational force based r-adaption with weighted Laplacian smoothing and mesh enrichment by h-refinement. A Zienkiewicz-Zhu best guess stress error estimator is used in the h-refinement strategy. The best sequence for combining the effectiveness of r- and h- adaption has been evolved at in this study. A further reduction in the potential energy and the relative error norm of the system is found to be achieved with combined r-adaption and mesh enrichment (in the form h-refinement). Numerical study confirms that the More >

D. P. Ghosh¹, S. Gopalakrishnan²

CMC-Computers, Materials & Continua, Vol.1, No.3, pp. 213-228, 2004, DOI:10.3970/cmc.2004.001.213

Abstract Anhysteretic, coupled, linear and nonlinear constitutive relationship for magnetostrictive material is studied in this paper. Constitutive relationships of magnetostrictive material are represented through two equations, one for actuation and other for sensing, both of which are coupled through magneto-mechanical coefficient. Coupled model is studied without assuming any explicit direct relationship with magnetic field. In linear-coupled model, which is assumed to preserve the magnetic flux line continuity, the elastic modulus, the permeability and magneto-elastic constant are assumed as constant. In nonlinear-coupled model, the nonlinearity is decoupled and solved separately for the magnetic domain and mechanical domain More >

European Cytokine Network, Vol.14, No.1, pp. 66-66, 2003

Abstract This article has no abstract. More >

Séverine Froget¹, Emmanuelle Barthelemy², François Guillot¹, Christophe Soler¹, Marie-Claude Coudert², Marc Benbunan², Christine Dosquet^2,3

European Cytokine Network, Vol.14, No.1, pp. 60-64, 2003

Abstract Cell and tissue therapy applications in humans are being used increasingly, particularly for tissue repair. Several reconstructed skin models have been proposed. Wound healing involves overlapping steps of inflammation, cell migration and proliferation, neovascularisation, extracellular matrix production and remo-delling. This is regulated by numerous cytokines and other soluble mediators. We have prepared dermal substitutes (DS) consisting of a collagen-GAG, three-dimensional matrix colonized by human dermal fibroblasts (HDF), isolated by skin explant or enzymatic digestion of the skin for potential therapeutic use in humans. To test the functionality of these DS, we measured (ELISA) the stimulatory… More >

Diane Damotte^1,3, Claire Goulvestre², Jeannine Charreire², Claude Carnaud¹

European Cytokine Network, Vol.14, No.1, pp. 52-59, 2003

Abstract Although adjuvants are essential for the initiation of experimental autoimmune diseases, their precise contribution to the pathological manifestations is still poorly understood. Experimental autoimmune thyroiditis (EAT) is interesting in that respect because it can be initiated with the help of two different adjuvants — Freund’s complete or LPS — which may initiate independent pathogenic pathways. In the present study, we have compared Freund’s-induced versus LPS-induced EAT with respect to their dependence upon CD8⁺ T cells, which are considered as major actors in the pathogenesis of thyroiditis. Our results reveal that whereas CD8+ T cells are mandatory More >