Michael L. Pianezza¹, Steven Rubin², Juan Bass², Shirley Chou², John G. Pike¹, Michael P. Leonard¹

Canadian Journal of Urology, Vol.11, No.1, pp. 2151-2156, 2004

Abstract Background: Wilms' Tumor is the most common malignant neoplasm of the urinary tract in children. Since 1969, the National Wilms' Tumor Study Group (NWTSG) has contributed to improving the clinical management and outcome of children affected by Wilms' Tumor. We have managed our patients according to NWTSG protocols and report our results herein.
Methods: Retrospective chart review of consecutive patients presenting at the Children's Hospital of Eastern Ontario (CHEO) with a diagnosis of Wilms' Tumor between April 1990 and March 2001.
Results: Forty patients with Wilms' Tumor (18 M/22 F) were diagnosed at CHEO during this interval. Mean… More >

Fred Saad¹, Kim Chi², Neil Fleshner³

Canadian Journal of Urology, Vol.11, No.5, pp. 2376-2382, 2004

Abstract Bone metastases are associated with significant skeletal-related morbidity that negatively correlates with quality of life and survival in patients with prostate cancer. Once prostate cancer has metastasized to bone, the median survival of patients is approximately 30 to 53 months; therefore, the chronic consequences of bone complications must be taken into consideration when developing long-term therapeutic strategies in this patient population. In addition to the bone-damaging effects of metastases, bone loss related to long-term hormonal therapy, as well as age-related bone loss, further compromise bone integrity in patients with advanced prostate cancer.
This article reviews the More >

Oren M. Shemtov¹, Sidney B. Radomski², Juanita Crook³

Canadian Journal of Urology, Vol.11, No.6, pp. 2450-2455, 2004

Abstract Purpose: We undertook to determine if any significant differences in the efficacy of sildenafil citrate for erectile dysfunction (ED) exists between patients who have received external beam radiation or brachytherapy for prostate cancer.
Materials and methods: Thirty-one patients who had received external beam radiation and nineteen patients who had received brachytherapy for prostate cancer and were subsequently treated with sildenafil citrate for post-irradiation ED comprised the patient population. A chart analysis was performed to determine either the presence or absence of concomitant risk factors for ED (coronary artery disease, diabetes, hypertension and smoking history) as well as… More >

C. D. GAMARRA-LUQUES, I. A. VEGA, E. KOCH, A. CASTRO-VAZQUEZ

BIOCELL, Vol.28, No.2, pp. 155-164, 2004, DOI:10.32604/biocell.2004.28.155

Abstract A new species of cyclopoid copepod, Ozmana huarpium, is described as a symbiont to Pomacea canaliculata (Lamarck 1822) (Caenogastropoda, Ampullariidae). Rather large numbers (about one hundred copepods per snail) were found, although there was no evidence of harm to the host. To our knowledge, O. haemophila (symbiont to P. maculata), and the currently described species, O. huarpium, are the only copepod species ever recorded as endosymbionts to freshwater invertebrates. While O. haemophila is restricted to the haemocoel of its host, O. huarpium predominate in the penis sheath, the ctenidium and the mantle cavity, figuring in these pallial organs 63-65 % of total More >

MOUYU YANG¹, V.BENNO MEYER-ROCHOW^1,2

BIOCELL, Vol.28, No.2, pp. 151-154, 2004, DOI:10.32604/biocell.2004.28.151

Abstract Only one insect (the scale insect Eriococcus sp.) is known, in which photoreceptive lamellae appear to have replaced the usual arthropod rhabdom microvilli. We are now reporting the presence of photoreceptive membranes, which also appear to resemble lamellae rather than microvilli, but they are in the ocellus of the tiny wasp Centrodora sp., which parasitizes scale insect eggs. The apparently optically homogenous lens of the Centrodora ocellus measures approximately 10 µm in diameter and, thus, operates at the limits of diffraction. We calculated that the lens is capable of focusing a parallel bundle of rays on the More >

Serge Carrier

Canadian Journal of Urology, Vol.10, Suppl.1, pp. 12-16, 2003

Abstract The phosphodiesterase enzymes, of at least 11 types, are ubiquitous throughout the body, and perform a variety of functions. Phosphodiesterase type 5 (PDE5) is the predominant enzyme in the corpus cavernosum, and plays a crucial role in penile erection. Inhibitors of PDE5 are the most effective oral agents in the treatment of erectile dysfunction. Sildenafil, tadalafil, and vardenafil are all potent inhibitors of PDE5 and show the same mechanism of action, although they have some pharmacological differences that may translate into varying clinical effects. More >

Todd M. Webster, Ronald G. Gerridzen

Canadian Journal of Urology, Vol.10, No.3, pp. 1905-1909, 2003

Abstract Introduction: Numerous management strategies are available for stress urinary incontinence, a significant problem for many women. The pubovaginal sling (PVS) with rectus fascia has proven efficacy with minimal morbidity. Historically, patients were admitted for an average of 4 days at the Ottawa Hospital. Since November 2001, patients have spent one night in hospital thereby cutting their total length of stay to less than 24 hours. This study assesses the feasibility of this approach.
Materials and methods: Ethics approval was obtained. All patient charts were reviewed retrospectively. Exclusion criteria included women booked for combined procedures or patient refusal.… More >

R. Yunes, G.F. Doncel, A.A. Acosta

BIOCELL, Vol.27, No.1, pp. 29-36, 2003, DOI:10.32604/biocell.2003.27.029

Abstract Our objective was to study the incidence of sperm-tail phosphotyrosine immunoreactivity in normozoospermic and asthenozoospermic human sperm samples, its association with sperm motion parameters, particularly hyperactivated motility, and its potential involvement in the pathogenesis of asthenozoospermia. The work was conducted as a prospective experimental study in the Sperm Biology and Andrology laboratories of the Jones Institute, a medical school-based fertility center. The study subjects were healthy fertile male donors (normozoospermic samples) and infertile patients (asthenozoospermic samples) attending the center. Recently ejaculated semen samples were washed twice to eliminate seminal plasma and a swim-up was performed… More >

MARÍA G. GARCÍA, CARLOS A. BUSSO, PABLO POLCI, NORBERTO L. GARCÍA GIROU, VIVIANA ECHENIQUE

BIOCELL, Vol.26, No.3, pp. 309-317, 2002, DOI:10.32604/biocell.2002.26.309

Abstract The effects of water stress on leaf water relations and growth are reported for three perennial tussock grass genotypes under glasshouse conditions. Studies were performed in genotypes El Palmar INTA and Selección Anguil of Agropyron scabrifolium (Döell) Parodi, and El Vizcachero of A. elongatum (Host) Beauv. Agropyron scabrifolium El Palmar INTA is native to a region with warm-temperate and humid climate without a dry season, and an average annual precipitation of 900 mm. Agropyron scabrifolium Selección Anguil comes from a region with a sub-humid, dry to semiarid climate and a mean annual precipitation of 600 mm. Agropyron elongatum is a… More >

LIDIA M. LOPEZ^*, AMANDA PELLEGRINO DE IRALDI^*, PATRICIA H. CARRIZO^**, MARTA DUBIN^**, ANDRÉS O.M. STOPPANI^**

BIOCELL, Vol.26, No.2, pp. 237-245, 2002, DOI:10.32604/biocell.2002.26.237

Abstract CG 10-248 (3,4-dihydro-2,2 dimethyl-9-chloro-2H-naphtho[1,2b]pyran-5,6-dione), a ß-lapachone analogue, modified the ultrastructure of rat liver mitochondria in vitro, in the absence of added oxidizable substrates. The condensed mitochondrial state was replaced by the orthodox or swollen state to a significant degree. The number of modified mitochondria depended on incubation time and quinone concentration, in the 25-100 µM range. Under the same experimental conditions, mitochondrial respiration was uncoupled as indicated by the increase in the rate of succinate oxidation by controlled mitochondria in metabolic state “4” (not in state “3”), and by the activation of latent F₀ F₁ -ATP synthase. More >